Table 1 Clinical and laboratory data for 296 patients with acute decompensated heart failure
Variable | HFpEF | HFrEF | P Value |
|---|---|---|---|
(n = 108) | (n = 188) | ||
Age (years) | 74.0 ± 10.2 | 73.3 ± 10.5 | 0.599 |
Male n, (%) | 77(71.3 %) | 118(62.8 %) | 0.161 |
History | |||
Coronary artery disease n, (%) | 58(53.7 %) | 96(51.25 %) | 0.717 |
Hypertension n, (%) | 79(73.1 %) | 132(70.2 %) | 0.689 |
Previous heart failure n, (%) | 62(57.4 %) | 90(47.9 %) | 0.118 |
Diabetes mellitus n, (%) | 49(45.4 %) | 100(53.2 %) | 0.227 |
COPD/asthma n, (%) | 27(25 %) | 40(21.3 %) | 0.474 |
Atrial fibrillation n, (%) | 35(32.4 %) | 55(29.3 %) | 0.601 |
Chronic renal insufficiency n, (%) | 22 (20.4 %) | 44 (23.4 %) | 0.883 |
Cardiac valvular disease n, (%) | 30(27.8 %) | 39(20.7 %) | 0.199 |
Intravenous medications during hospitalization | |||
Diuretics n, (%) | 97(89.8 %) | 172(91.5 %) | 0.677 |
Cedilanid n, (%) | 38(35.2 %) | 89(47.3 %) | 0.051 |
Nitroglycerin n, (%) | 10(9.3 %) | 59(31.4 %) | 0.522 |
Nitroprusside n, (%) | 10(9.3 %) | 23(12.2 %) | 0.565 |
Oral medications during hospitalization | |||
ACE inhibitors n, (%) | 61(56.5 %) | 121(64.4 %) | 0.215 |
ARB n, (%) | 23(21.3 %) | 30(16.0 %) | 0.272 |
Beta-blocker n, (%) | 73(67.6 %) | 141(75 %) | 0.180 |
Calcium channel blocker n, (%) | 19(17.6 %) | 42(22.3 %) | 0.372 |
Digoxin n, (%) | 47(43.5 %) | 110(58.5 %) | 0.016 |
Diuretics n, (%) | 68(63.0 %) | 38(20.2 %) | 0.462 |
Warfarin n, (%) | 25(23.1 %) | 50(26.6 %) | 0.579 |
Death n, (%) | 6(5.6 %) | 15(8.0 %) | 0.490 |
Admission SBP (mmHg) | 155.0 ± 28.5 | 144.6 ± 29.7 | 0.003 |
Admission DBP (mmHg) | 80.4 ± 15.2 | 78.3 ± 13.8 | 0.556 |
BMI (kg/m2) | 23.5 ± 2.8 | 23.1 ± 2.6 | 0.354 |
HR (bpm) | 90.0 ± 17.2 | 89.4 ± 19.0 | 0.677 |
HIF-1α(ng/ml) | 2.70 ± 0.78 | 3.37 ± 0.79 | 0.001 |
NT-proBNP(ng/L) | 6826.7 ± 7049.4 | 9297.7 ± 8359.8 | 0.007 |
TnT(ng/L) | 85.5 ± 163.5 | 143.4 ± 241.1 | 0.015 |
hs-CRP (mg/l) | 8.5 ± 5.7 | 9.2 ± 7.1 | 0.059 |
D-dimer (ng/ml) | 294.4 ± 486.8 | 242.7 ± 312.3 | 0.302 |
Creatinine (ummol/l) | 98.0 ± 45.4 | 100.8 ± 56.6 | 0.744 |
UA (ummol/l) | 407.3 ± 137.4 | 389.2 ± 147.4 | 0.644 |
BUN(mmol/L) | 10.2 ± 4.5 | 9.8 ± 5.1 | 0.521 |