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Table 2 Depression severity and intensity, as measured with HDRS-17 and MADRS scales (mean ± sd) and evolution of the inflammatory profile, as measured by hsCRP and fibrinogen levels, according to the depression status over a 9-month follow-up period after an ACS

From: High sensitivity C reactive protein, fibrinogen levels and the onset of major depressive disorder in post-acute coronary syndrome

 

D7

M1

M3

M9

 

No Depression 71.3%

Depression 28.7%

No Depression 71.3%

Depression 28.7%

No Depression 71.3%

Depression 28.7%

No Depression 71.3%

Depression 28.7%

MADRS

5.5 ± 3

6.9 ± 4

5.7 ± 4

13.9 ± 8*

6.2 ± 4

18.2 ± 8**

5.5 ± 5

21.0 ± 8**

HDRS-17

6.7 ± 3

9.2 ± 4

9.0 ± 5

14.0 ± 7*

8.6 ± 5

17.2 ± 7*

7.5 ± 5

20.1 ± 5**

hs-CRP (mg/l)

8.7 ± 8.0

10.1 ± 11.0

2.30 ± 2.3

3.05 ± 4.2

2.12 ± 2.5

2.27 ± 3.8

2.65 ± 6.4

2.46 ± 3.4

Fibrinogen (g/l)

5.22 ± 1.1

5.62 ± 1.2*

3.97 ± 0.7

4.18 ± 1.1

3.65 ± 0.6

3.62 ± 1.0

3.69 ± 0.8

4.16 ± 0.8*

  1. *p values of tests comparing the “No depression” and “Depression” groups (Student’s t test for age, Chi square tests for proportions). *p < 0.05; **p < 0.01.