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Table 2 Depression severity and intensity, as measured with HDRS-17 and MADRS scales (mean ± sd) and evolution of the inflammatory profile, as measured by hsCRP and fibrinogen levels, according to the depression status over a 9-month follow-up period after an ACS

From: High sensitivity C reactive protein, fibrinogen levels and the onset of major depressive disorder in post-acute coronary syndrome

  D7 M1 M3 M9
  No Depression 71.3% Depression 28.7% No Depression 71.3% Depression 28.7% No Depression 71.3% Depression 28.7% No Depression 71.3% Depression 28.7%
MADRS 5.5 ± 3 6.9 ± 4 5.7 ± 4 13.9 ± 8* 6.2 ± 4 18.2 ± 8** 5.5 ± 5 21.0 ± 8**
HDRS-17 6.7 ± 3 9.2 ± 4 9.0 ± 5 14.0 ± 7* 8.6 ± 5 17.2 ± 7* 7.5 ± 5 20.1 ± 5**
hs-CRP (mg/l) 8.7 ± 8.0 10.1 ± 11.0 2.30 ± 2.3 3.05 ± 4.2 2.12 ± 2.5 2.27 ± 3.8 2.65 ± 6.4 2.46 ± 3.4
Fibrinogen (g/l) 5.22 ± 1.1 5.62 ± 1.2* 3.97 ± 0.7 4.18 ± 1.1 3.65 ± 0.6 3.62 ± 1.0 3.69 ± 0.8 4.16 ± 0.8*
  1. *p values of tests comparing the “No depression” and “Depression” groups (Student’s t test for age, Chi square tests for proportions). *p < 0.05; **p < 0.01.