Association of adiponectin with type 2 diabetes and hypertension in African American men and women: the Jackson Heart Study

Table 5 Association between adiponectin ^a and hypertension using crude and adjusted logistic regression among men and women (N = 3,663)

	Men (N = 1,334)		Women (N = 2,329)
Predictor	Odds ratio (95% confidence interval)	P-value	Odds ratio (95% confidence interval)	P-value
Adiponectin Q1^b	0.69 (0.49, 0.97)	.03	0.90 (0.70, 1.16)	.41
Adiponectin Q2	0.70 (0.48, 1.00)	.05	0.90 (0.72, 1.13)	.36
Adiponectin Q3	0.75 (0.51, 1.10)	.13	0.95 (0.76, 1.18)	.64
Q4	1.0		1.0
Adiponectin Q1^c	1.07 (0.73, 1.58)	.72	1.39 (1.05, 1.85)	.02
Adiponectin Q2	0.94 (0.63, 1.41)	.76	1.32 (1.02, 1.70)	.04
Adiponectin Q3	0.92 (0.60, 1.40)	.68	1.13 (0.88, 1.45)	.34
Q4	1.0		1.0
Adiponectin Q1^d	0.79 (0.49, 1.26)	.32	0.67 (0.46, 0.96)	.03
Adiponectin Q2	0.75 (0.47, 1.20)	.23	0.86 (0.63, 1.16)	.32
Adiponectin Q3	0.85 (0.53, 1.37)	.51	0.86 (0.65, 1.13)	.28
Q4	1.0		1.0
Adiponectin Q1^e	0.79 (0.49, 1.26)	.33	0.66 (0.46, 0.95)	.03
Adiponectin Q2	0.75 (0.47, 1.19)	.22	0.85 (0.63, 1.16)	.33
Adiponectin Q3	0.85 (0.53, 1.37)	.51	0.85 (0.64, 1.13)	.28
Q4	1.0		1.0
Adiponectin Q1^f	0.80 (0.50, 1.28)	.36	0.66 (0.46, 0.95)	.02
Adiponectin Q2	0.75 (0.47, 1.20)	.23	0.86 (0.63, 1.16)	.32
Adiponectin Q3	0.86 (0.53, 1.38)	.52	0.85 (0.64, 1.12)	.25
Q4	1.0		1.0

^aAdiponectin in quartiles (Q = quartile): 1) Q1 = ≤2.70 ug/mL, 2) Q2 = >2.70 – ≤4.2 ug/mL, 3)Q3 = >4.2 – ≤ 6.7 ug/mL, 4) Q4 > 6.7 ug/mL. The referent group is Q4 > 6.7 ug/mL.
^b = Model 1, crude.
^c = Model 2, partly adjusted for age.
^d = Model 3, partly adjusted for age, fasting insulin, HOMA-IR(Insulin resistance), low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, total cholesterol, c-reactive protein, plasma leptin.
^e = Model 4, partly adjusted for age, body mass index, smoking status, physical activity score, alcohol consumption status.
^f = Model 5, fully adjusted for age, body mass index, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, total cholesterol, plasma leptin, fasting insulin, HOMA-IR, C-reactive protein, smoking status, physical activity score, alcohol consumption status, and socioeconomic status based on annual household income.
A two-tailed level of significance was established as P < .05.

ISSN: 1471-2261