Association of adiponectin with type 2 diabetes and hypertension in African American men and women: the Jackson Heart Study

Table 4 Association between adiponectin ^a and type 2 diabetes using crude and adjusted logistic regression among men and women (N = 3,663)

	Men (N = 1,334)		Women (N = 2,329)
Predictor	Odds ratio (95% confidence interval)	P-value	Odds ratio (95% confidence interval)	P-value
Adiponecin Q1^b	0.81 (0.51, 1.31)	.39	1.67 (1.22, 2.28)	.001
Adiponectin Q2	0.71 (0.43, 1.19)	.19	1.13 (0.83, 1.53)	.44
Adiponectin Q3	0.71 (0.41, 1.22)	.21	0.94 (0.69, 1.28)	.70
Q4	1.0		1.0
Adiponectin Q1^c	1.12 (0.68, 1.83)	.65	2.19 (1.58, 3.03)	<.0001
Adiponectin Q2	0.88 (0.52, 1.48)	.62	1.42 (1.03, 1.95)	.04
Adiponectin Q3	0.82 (0.47, 1.43)	.49	1.03 (0.76, 1.41)	.83
Q4	1.0		1.0
Adiponectin Q1^d	0.70 (0.40, 1.21)	.20	1.47 (1.02, 2.12)	.03
Adiponectin Q2	0.64 (0.37, 1.12)	.12	1.10 (0.79, 1.55)	.58
Adiponectin Q3	0.64 (0.36, 1.14)	.13	0.86 (0.62, 1.20)	.38
Q4	1.0		1.0
Adiponectin Q1^e	1.13 (0.69, 1.85)	.63	2.19 (1.58, 3.03)	<.0001
Adiponectin Q2	0.87 (0.52, 1.48)	.61	1.41 (1.03, 1.94)	.03
Adiponectin Q3	0.83 (0.48, 1.45)	.51	1.02 (0.75, 1.39)	.90
Q4	1.0		1.0
Adiponectin Q1^f	0.75 (0.43, 1.30)	.30	1.47 (1.02, 2.11)	.04
Adiponectin Q2	0.65 (0.37, 1.14)	.13	1.10 (0.78, 1.55)	.58
Adiponectin Q3	0.64 (0.36, 1.16)	.14	0.86 (0.62, 1.22)	.36
Q4	1.0		1.0

^aAdiponectin in quartiles (Q = quartile): 1) Q1 = ≤2.70 ug/mL, 2) Q2 = >2.70 – ≤4.2 ug/mL, 3)Q3 = >4.2 – ≤6.7 ug/mL, 4) Q4 > 6.7 ug/mL. The referent group is Q4 > 6.7 ug/mL.
^bModel 1, crude.
^cModel 2, partly adjusted for age.
^dModel 3, partly adjusted for age, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, total cholesterol, c-reactive protein, plasma leptin.
^eModel 4, partly adjusted for age, body mass index, smoking status, physical activity score and alcohol consumption status.
^fModel 5, fully adjusted for age, body mass index, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, total cholesterol, plasma leptin, C-reactive protein, smoking status, physical activity score, alcohol consumption status and socioeconomic status based on annual household income.
A two-tailed level of significance was established as P < .05.

ISSN: 1471-2261