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Table 3 Association between lipid parameters and carotid plaque outcomes, adjusted for demographics and vascular risk factorsa

From: Lipids and carotid plaque in the Northern Manhattan Study (NOMAS)

  OR (95% CI)bvs. No plaque
  Plaque Multiple plaques Thickness >1.9 mm Irregular plaque
Total cholesterol 1.12 (1.01-1.25) 1.15 (1.02-1.30) 1.11 (0.97-1.27) 1.08 (0.91-1.28)
LDL 1.14 (1.02-1.27) 1.16 (1.03-1.31) 1.13 (0.99-1.29) 1.09 (0.91-1.29)
HDL 0.97 (0.86-1.09) 0.91 (0.79-1.05) 0.96 (0.83-1.11) 1.10 (0.90-1.33)
Triglycerides 0.99 (0.88-1.10) 1.04 (0.92-1.18) 1.01 (0.88-1.16) 0.97 (0.81-1.17)
Non-HDL 1.13 (1.01-1.26) 1.17 (1.03-1.33) 1.12 (0.98-1.28) 1.07 (0.90-1.28)
Lp(a) 1.21 (0.99-1.48) 1.31 (1.03-1.66) 1.22 (0.94-1.58) 1.05 (0.55-1.99)
ApoB 1.29 (1.03-1.60) 1.29 (1.00-1.66) 1.35 (1.04-1.75) 1.56 (0.95-2.56)
ApoA-I 0.85 (0.70-1.05) 0.76 (0.60-0.97) 0.80 (0.63-1.03) 0.83 (0.48-1.41)
T-CHOL:HDL 1.13 (1.01-1.26) 1.23 (1.08-1.40) 1.16 (1.01-1.33) 1.00 (0.83-1.19)
LDL:HDL 1.16 (1.04-1.29) 1.25 (1.10-1.41) 1.18 (1.03-1.36) 1.03 (0.86-1.23)
ApoB:ApoA-I 1.35 (1.08-1.69) 1.49 (1.15-1.94) 1.41 (1.08-1.84) 1.46 (1.06-2.01)
  1. aage, sex, race/ethnicity, hypertension, diabetes, BMI, pack-years of cigarette smoking, pipe or cigar smoking (past/current/never), moderate alcohol use, moderate to heavy physical activity, and the change in time between lipid and plaque measurements
  2. b1 SD increase