Skip to main content

Table 3 Association between lipid parameters and carotid plaque outcomes, adjusted for demographics and vascular risk factorsa

From: Lipids and carotid plaque in the Northern Manhattan Study (NOMAS)

 

OR (95% CI)bvs. No plaque

 

Plaque

Multiple plaques

Thickness >1.9 mm

Irregular plaque

Total cholesterol

1.12 (1.01-1.25)

1.15 (1.02-1.30)

1.11 (0.97-1.27)

1.08 (0.91-1.28)

LDL

1.14 (1.02-1.27)

1.16 (1.03-1.31)

1.13 (0.99-1.29)

1.09 (0.91-1.29)

HDL

0.97 (0.86-1.09)

0.91 (0.79-1.05)

0.96 (0.83-1.11)

1.10 (0.90-1.33)

Triglycerides

0.99 (0.88-1.10)

1.04 (0.92-1.18)

1.01 (0.88-1.16)

0.97 (0.81-1.17)

Non-HDL

1.13 (1.01-1.26)

1.17 (1.03-1.33)

1.12 (0.98-1.28)

1.07 (0.90-1.28)

Lp(a)

1.21 (0.99-1.48)

1.31 (1.03-1.66)

1.22 (0.94-1.58)

1.05 (0.55-1.99)

ApoB

1.29 (1.03-1.60)

1.29 (1.00-1.66)

1.35 (1.04-1.75)

1.56 (0.95-2.56)

ApoA-I

0.85 (0.70-1.05)

0.76 (0.60-0.97)

0.80 (0.63-1.03)

0.83 (0.48-1.41)

T-CHOL:HDL

1.13 (1.01-1.26)

1.23 (1.08-1.40)

1.16 (1.01-1.33)

1.00 (0.83-1.19)

LDL:HDL

1.16 (1.04-1.29)

1.25 (1.10-1.41)

1.18 (1.03-1.36)

1.03 (0.86-1.23)

ApoB:ApoA-I

1.35 (1.08-1.69)

1.49 (1.15-1.94)

1.41 (1.08-1.84)

1.46 (1.06-2.01)

  1. aage, sex, race/ethnicity, hypertension, diabetes, BMI, pack-years of cigarette smoking, pipe or cigar smoking (past/current/never), moderate alcohol use, moderate to heavy physical activity, and the change in time between lipid and plaque measurements
  2. b1 SD increase