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Table 4 Vascular outcome measurements

From: The effect of long-term homocysteine-lowering on carotid intima-media thickness and flow-mediated vasodilation in stroke patients: a randomized controlled trial and meta-analysis

 

Placebo (n = 79)

Vitamins (n = 83)

p

Vascular Structure

   

Carotid intima-medial thickness (mm)

0.83 ± 0.18

0.84 ± 0.17

0.74

Carotid lumen diameter (mm)

6.35 ± 0.72

6.49 ± 0.94

0.31

Brachial artery diameter (mm)

3.66 ± 0.67

3.84 ± 0.82

0.12

Vascular Function

   

Flow-mediated dilation (%)

3.0 (0.6 – 6.6)

4.0 (0.9 – 7.2)

0.48

GTN-mediated dilation (%)

20.2 ± 7.4

20.2 ± 8.1

0.98

  1. GTN indicates glyeryl trinitrate.
  2. Values are mean ± standard deviation or median (inter-quartile range)
  3. P-values are from a two-sample t-test or a two-sample rank test (Mann-Whitney)