Figure 3

Change in CIMT associated with B-vitamin treatment in all randomised trials published to date. Squares indicate the mean difference in CIMT between the vitamin-treated and placebo-treated groups: the size of the square is proportional to the number of subjects in the study and the horizontal line indicates the 95% confidence interval. Diamonds represent the 95% confidence intervals for the sub-total and total differences. Studies are ordered by effect size. WMD, weighted mean difference; CI, confidence interval; RF indicates subjects with renal failure as defined by authors; RTR, renal transplant recipients; CAD, coronary artery disease [5–7, 28, 33, 34]