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Table 1 Difference in clot lysis following continuous-wave ultrasound exposure.

From: Changes in clot lysis levels of reteplase and streptokinase following continuous wave ultrasound exposure, at ultrasound intensities following attenuation from the skull bone

Intensity (W/cm2)

Time (Min)

US+SK (n = 6)

Control (n = 6)

P-value

US+r-PA (n = 6)

Control (n = 6)

P-value

0.0125

      

20

13 (11–29)

13 (11–29)

0.69

7 (5–11)

6 (4 – 9)

0.08

40

27 (19–47)

23 (21–36)

0.25

16 (9–22)

12 (7–25)

0.25

60

43 (22–59)

31 (23–54)

0.12

22 (14–42)

22 (10–43)

0.46

0.025

      

20

15 (13–26)

16 (13–31)

0.34

9 (5–12)

7 (3–10)

0.25

40

25 (18–33)

22 (19–40)

0.60

16 (10–19)

15 (7–17)

0.17

60

34 (21–58)

30 (23–49)

0.25

36 (13–37)

27 (10–37)

0.12

0.05

      

20

15 (12–27)

17 (15–21)

0.69

8 (4–10)

7 (5–10)

0.46

40

21 (18–35)

25 (21–36)

0.08

16 (13–19)

12 (11–22)

0.34

60

39 (28–52)

36 (27–52)

0.46

26 (20–30)

24 (17–28)

<0.05

0.1

      

20

18 (13–27)

15 (10–31)

0.69

7 (6–10)

8 (4–9)

0.50

40

22 (19–37)

21 (15–42)

0.35

15 (10–18)

17 (3–12)

0.92

60

32 (25–46)

29 (20–49)

0.35

28 (23–34)

24 (13–39)

0.60

0.15

      

20

17 (14–27)

17 (13–24)

0.60

7 (5–11)

7 (5–8)

0.25

40

28 (19–38)

23 (16–34)

0.17

15 (14–17)

15 (11–18)

0.60

60

35 (21–44)

39 (23–49)

0.12

28 (20–41)

25 (16–37)

0.75

0.3

      

20

16 (14–17)

17 (13–25)

0.69

8 (3–12)

7 (2–11)

0.12

40

26 (19–48)

25 (18–35)

0.25

14 (12–29)

13 (8–21)

< 0.05

60

38 (37–58)

35 (22–62)

0.46

30 (24–51)

22 (15–39)

< 0.05

0.6

      

20

14 (5–16)

13 (9–16)

0.92

29 (18–35)

25 (18–31)

0.08

40

19 (10–23)

17 (12–21)

0.60

31 (19–52)

27 (16–43)

< 0.05

60

23 (14–26)

21 (16–26)

0.92

41 (28–57)

33 (22–44)

< 0.05

0.9

      

20

26 (18–29)

27 (22–31)

< 0.05

23 (18–29)

20 (14–29)

<0.05

40

34 (30–42)

36 (27–42)

< 0.05

44 (31–47)

39 (25–42)

< 0.05

60

38 (30–42)

42 (33–51)

< 0.05

50 (43–60)

43 (39–45)

< 0.05

1.2

      

20

26 (22–29)

29 (26–34)

< 0.05

17 (14–23)

9 (8–10)

< 0.05

40

32 (28–33)

35 (30–38)

< 0.05

36 (26–38)

21 (19–22)

< 0.05

60

32 (30–37)

41 (37–44)

< 0.05

42 (36–48)

32 (25–35)

< 0.05

  1. Clot lysis (%) of clots exposed to streptokinase concomitantly with continuous-wave ultrasound at different intensities (n = 6 for each intensity) for one hour (US+SK) and clots exposed to streptokinase alone (n = 6 for each intensity, (control clots)) and in clots exposed to reteplase concomitantly with continuous-wave ultrasound at different intensities (n = 6 for each intensity) for one hour (US-r-PA) and reteplase alone (n = 6 for each intensity, (control clots)). Results are presented as medians and 5th – 95th percentiles. Wilcoxon's signed rank test was used to assess statistical difference.
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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