Figure 8

Plasma levels of specific cytokines related to the immune response in atherosclerosis. Cytokine array results show the changes of the cytokines IL-12 (A), IL-4 (B), and IFNγ (C) in the plasma of hApoB100 transgenic mice that were exposed to SSW smoke. The cytokines in the plasma were captured by antibodies coated on the bottom of 96-well plates (Quansys Biosciences, Utah, USA). After washing, probing with streptavidin-HRP, and reacting with substrate, the images were captured with CCD camera (Roper Micromax 1300B). The strength of signal was translated into concentration of cytokine by plotting against a standard curve.