Figure 3
From: Estrogen-induced DNA synthesis in vascular endothelial cells is mediated by ROS signaling
Glutathione peroxidase mimic inhibits the formation of estrogen-induced reactive oxygen species. Pretreatment with the glutathione peroxidase mimic ebselen showed a significant reduction of E2-induced oxidants in endothelial cells. Data from three independent experiments are presented as ROS production with controls set at 100% (± SD). Values that are significantly different from E2 treatment alone (P < 0.05) are indicated with an asterisk (*).