Table 3 Distribution of factors and relation to cardiovascular events during follow-up and partly and fully adjusted hazard ratios for cardiovascular events associated with Interleukin-1 receptor antagonist gene polymorphisms (IL-1RA) and serostatus of CMV

- other^d

20.4%

1^reference

1^reference

- Il-1RN*2

16.3% (0.73)

1.1 (0.80–1.66)

1.03 (0.60–1.76)

CMV-serostatus

- negative

20.7%

1^reference

1^reference

- positive

0.91 (0.55–1.52)

1.00 (0.59–1.72)

   - positive, titre < median

16.7%

0.74 (0.38–1.43)

0.78 (0.40–1.54)

   - positive titre ≥ median

22.1% (0.54)

1.12 (0.61–2.05)

1.32 (0.69–2.52)

IL-1 RA and CMV serostatus

- IL-other^d and CMV-negative

21.9%

1^reference

1^reference

- IL-other^d and CMV-positive

19.1%

0.86 (0.50–1.45)

0.94 (0.54–1.64)

- Il-1RN*2 and CMV-negative

12.5%

0.56 (0.13–2.36)

0.37 (0.08 – 1.67)

- Il-1RN*2 and CMV-positive

21.4% (0.83)

0.96 (0.32–3.43)

0.95 (0.27 – 3.38)