Figure 6

Insertional polymorphisms in rat Abcg8 exon 13. Panel A shows the sizes of PCR products amplified using primers that amplify the 3'-UTR of Abcg8. Two distinct products of 1.11 Kb and 1.252 Kb bands were noted. SD and WKA were homozygous for the 1.11 kb size, while WKY, SHR and SHRSP were homozygous for the 1.25 kb size. Interestingly, the sample from a Wistar rat was heterozygous for this change. Direct sequencing of the larger product showed a 143 bp insertion at position 2099 in the 3' UTR of Abcg8 (panel B).