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Table 1 Definitions of electrocardiographic and echocardiographic parameters used in this study

From: Electrocardiographic features of disease progression in arrhythmogenic right ventricular cardiomyopathy/dysplasia

Variables

Definitions

Epsilon wave (major depolarization criterion)

Distinct waves of small amplitude that occupy the ST segment in right precordial leads (V1-V3) and are distinct from the QRS complex

Terminal activation duration (minor depolarization criterion)

Longest value in V1 through V3 from the nadir of the S wave to the end of all depolarization

T wave inversion

Any T wave negativity

Inferior leads T wave inversion

Inverted T waves in 2 out of 3 inferior leads (II, III, and aVF)

Major repolarization criteria

Inverted T waves in right precordial leads (V1, V2, and V3) or beyond in individuals >14 years of age (in the absence of complete right bundle branch block)

Minor repolarization criteria

- Inverted T waves in leads V1 and V2 in individuals >14 years of age (in the absence of complete right bundle branch block) or in V4, V5, or V6

- Inverted T waves in leads V1, V2, V3, and V4 in individuals >14 years of age in the presence of complete right bundle branch block

Complete right bundle branch block

QRSd ≥120 ms and:

A1: R’ or r’ in V1 or V2

A2: S duration > R duration in I and V6

A3: S duration >40 ms in I and V6

A4: R peak time >50 ms in V1 or V2

a: A1 + A2

b: A1+ A3

c: A4+ (A2 or A3)

Incomplete right bundle branch block

QRS <120 ms and R peak time in V1 or V2 > 50 ms

QRS notching

Additional deflections/notches at the beginning of the QRS, on top of the R-wave, or in the nadir of the S-wave in the absence of bundle branch block

Left ventricular involvement

Echocardiographic documentation of LV wall motion abnormalities or a reduced ejection fraction (<50%) in the absence of other causes

Right ventricular regional wall motion abnormalities

Echocardiographic documentation of regional right ventricular akinesia/dyskinesia