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Table 1 Definitions of electrocardiographic and echocardiographic parameters used in this study

From: Electrocardiographic features of disease progression in arrhythmogenic right ventricular cardiomyopathy/dysplasia

Variables Definitions
Epsilon wave (major depolarization criterion) Distinct waves of small amplitude that occupy the ST segment in right precordial leads (V1-V3) and are distinct from the QRS complex
Terminal activation duration (minor depolarization criterion) Longest value in V1 through V3 from the nadir of the S wave to the end of all depolarization
T wave inversion Any T wave negativity
Inferior leads T wave inversion Inverted T waves in 2 out of 3 inferior leads (II, III, and aVF)
Major repolarization criteria Inverted T waves in right precordial leads (V1, V2, and V3) or beyond in individuals >14 years of age (in the absence of complete right bundle branch block)
Minor repolarization criteria - Inverted T waves in leads V1 and V2 in individuals >14 years of age (in the absence of complete right bundle branch block) or in V4, V5, or V6
- Inverted T waves in leads V1, V2, V3, and V4 in individuals >14 years of age in the presence of complete right bundle branch block
Complete right bundle branch block QRSd ≥120 ms and:
A1: R’ or r’ in V1 or V2
A2: S duration > R duration in I and V6
A3: S duration >40 ms in I and V6
A4: R peak time >50 ms in V1 or V2
a: A1 + A2
b: A1+ A3
c: A4+ (A2 or A3)
Incomplete right bundle branch block QRS <120 ms and R peak time in V1 or V2 > 50 ms
QRS notching Additional deflections/notches at the beginning of the QRS, on top of the R-wave, or in the nadir of the S-wave in the absence of bundle branch block
Left ventricular involvement Echocardiographic documentation of LV wall motion abnormalities or a reduced ejection fraction (<50%) in the absence of other causes
Right ventricular regional wall motion abnormalities Echocardiographic documentation of regional right ventricular akinesia/dyskinesia