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Table 3 Changes in LRNC and carotid arterial wall burden

From: Early decrease in carotid plaque lipid content as assessed by magnetic resonance imaging during treatment of rosuvastatin

  Baseline 3 Months 12 Months 24 Months
LRNC, mm3 111.5 ± 104.2 103.6 ± 95.8* 101.7 ± 93.4* 97.7 ± 91.5*
LRNC% 18.9% ± 11.9% 17.9% ± 11.5%* 17.5% ± 11.2%* 16.7% ± 11.3%*
Wall volume, mm3 533.3 ± 208.9 523.1 ± 196.3 521.0 ± 194.2 528.0 ± 198.9
Lumen volume, mm3 522.1 ± 246.7 514.0 ± 234.2 512.1 ± 245. 6 537.6 ± 265.0
PWV, % 51.0% ± 8.2% 50.8% ± 8.5% 50.9% ± 9.0% 50.3% ± 8.6%
  1. Data are presented as mean ± SD. Changes over time in plaque measurements were compared to baseline using the paired t-test (LRNC, LRNC % and lumen volume were logarithmically transformed to normalize their distributions). LRNC = lipid-rich necrotic core; % LRNC = proportion of LRNC relative to the wall area; PWV = percent wall volume. * P < 0.05 when compared to baseline.