Table 3 Results of meta-analysis in each group and mean CAP volume in each group at baseline and follow up

≤70 mg

7 (1250)

177.1±41.9

125.9±38.6

-0.156 (-0.235~ -0.078, 0.000)

0.57 (0.997)

0

-0.146 (-0.238~ -0.054)

-0.167 (-0.270~ -0.064)

0.835

Without 2006 ASTEROID Ros

Without 2011 SATURN Ros

>70≤100HP mg

11 (1352)

129.7±72.3

123.8±69.8

-0.123 (-0.199~ -0.048, 0.001)

6.83 (0.741)

0

-0.103 (-0.182~ -0.024)

-0.151 (-0.235~ -0.067)

0.501

Without 2009 JAPAN-ACS Ato

Without 2004 REVERSAL Ato

>70≤100MP mg

5 (1548)

195.8±2.3

191.8±4.7

-0.045 (-0.115~ -0.026, 0.215)

1.59 (0.811)

0

-0.016 (-0.103~ -0.066)

-0.061 (-0.140~ -0.019)

0.500

Without 2007 ILLUSTRATE Ato+Tor

Without 2008 STRADIVARIUS Con

>70≤100LP mg

6 (1061)

201.2±15.1

197.3±15.0

-0.045 (-0.130~0.040, 0.301)

1.14 (0.950)

0

-0.024 (-0.136~ 0.087)

-0.059 (-0.148~ 0.031)

0.241

Without 2007 ILLUSTRATE Ato

Without 2004 A-PLUS Ava 50

>100 mg

10 (669)

175.9±86.4

178.7±89.1

0.017 (-0.090~0.124, 0.757)

2.37 (0.984)

0

-0.000 (-0.135~ 0.136)

0.039 (-0.073~ 0.151)

0.692

Without 2004 REVERSAL Pro

Without 2005 Tani S Pra

<0%

8 (1276)

201.2±13.8

198.3±13.8

-0.034 (-0.111~ 0.044, 0.396)

1.55 (0.981)

0

-0.012 (-0.109~ 0.084)

-0.044 (-0.125~ 0.037)

0.087

Without 2007 ILLUSTRATE Ato

Without 2004 A-PLUS Ava 50

>0≤30%

13 (2014)

188.6±51.7

186.3±52.7

-0.032 (-0.093~ 0.030, 0.315)

4.59 (0.970)

0

-0.010 (-0.080~ 0.061)

-0.042 (-0.108~ 0.024)

0.537

Without 2007 ILLUSTRATE Ato+Tor

Without 2004 REVERSAL Pra

>30≤40%

10 (594)

102.9±96.9

94.3±90.4

-0.199 (-0.314~ -0.085, 0.001)

3.10 (0.960)

0

-0.166 (-0.295~ -0.038)

-0.214 (-0.342~ -0.085)

0.024

Without 2009 JAPAN-ACS Ato

Without 2009 COSMOS Ros

>40≤50%

8 (1677)

157.8±37.8

150.7±36.3

-0.108 (-0.176~ -0.040, 0.002)

2.50 (0.927)

0

-0.093 (-0.174~ -0.011)

-0.126 (-0.200~ -0.053)

0.605

Without 2011 SATURN Ros

Without 2004 REVERSAL Ato

>50%

1 (349)

212.2±81.3

197.5±79.1

-0.183 (-0.332~ -0.035, 0.016)