Figure 4From: Left ventricular torsional mechanics and myocardial iron load in beta-thalassaemia major: a potential role of titin degradation Gel electrophoresis for analysis of titin degradation in ventricular tissue obtained from control (CTRL) and iron overloaded (IO) mice. Ventricular myocardium of IO mice showed significant reduction of T1/(myosin heavy chain) MHC and increase in T2/MHC ratios and the appearance of a faint titin degradation subfragment (arrow). (*p < 0.05 vs controls).Back to article page