Table 6 Effects of the study drugs on blood pressure (mmHg), HR (bpm) and plasma creatinine (μmol/L)
Parameters | High BNP group | Extra-high BNP group | ||||||
|---|---|---|---|---|---|---|---|---|
Dobutamine (n = 30) | rhBNP (n = 28) | Dobutamine (n = 23) | rhBNP (n = 23) | |||||
Baseline | 5 Days | Baseline | 5 Days | Baseline | 5 Days | Baseline | 5 Days | |
SBP | 119.3 ± 12.7 | 121.3 ± 12.0 | 122.9 ± 11.9 | 115.4 ± 12.4** | 114.8 ± 11.9 | 116.0 ± 12.5 | 118.6 ± 13.0 | 113.2 ± 13.2** |
DBP | 72.4 ± 6.8 | 74.3 ± 5.3 | 73.5 ± 7.7 | 69.6 ± 7.9** | 70.7 ± 6.7 | 71.8 ± 6.6 | 71.9 ± 6.5 | 68.7 ± 6.6** |
HR | 77.6 ± 12.5 | 80.3 ± 13.1 | 81.8 ± 11.1 | 83.9 ± 11.5 | 83.2 ± 13.9 | 85.7 ± 13.0 | 82.3 ± 12.4 | 84.6 ± 9.3 |
Cr | 84.4 ± 29.8 | 79.3 ± 20.4 | 78.5 ± 31.9 | 80.9 ± 26.3 | 95.4 ± 24.4 | 90.3 ± 23.3 | 98.6 ± 30.1 | 105.5 ± 32.9 |