Figure 2

MEK1-ERK1/2-GATA4 signaling pathway in male young exposure to SHS promotes left ventricular concentric hypertrophy. (A). Western blot analysis of p-MEK1, MEK 1, p-ERK1/2, ERK1/2 and GATA4 protein expression in the MYC, MYS, MOC and MOS groups. (B). Quantification of densitometry analysis of protein expression levels. Statistical analysis of the p-MEK1/MEK1 and p-ERK1/2/ERK1/2 ratios and GATA4 densitometry in MYC, MYS, MOC and MOS groups. All data are presented as means ± SD. *p < 0.05, **p < 0.01 significantly statistical differences compared with male young control (MYC). *p < 0.05, **p < 0.01 significantly statistical differences compared with male old control (MOC).