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Table 1 Patient characteristics at baseline

From: Clinical course and outcomes of type-2 diabetic patients after treatment intensification for insufficient glycaemic control - results of the 2 year prospective DiaRegis follow-up

 

Patients included (n = 3810)

Patients with a 2 year FU* (n = 3058)

Age (years)

65.9 (57.6–72.9)

66.1 (57.7–72.9)

Female gender (%)

46.7

46.7

Body weight (kg)

88 (78–100)

88 (78–100)

Diabetes duration (years)

5.5 (2.9–9.4)

5.6 (2.9–9.4)

Lipid values

  

 LDL-C (mg/dL)

120 (98–145)

119 (96–145)

 HDL-C (mg/dL)

47 (40–57)

47 (40–56)

 TG (mg/dL)

176 (127–242)

175 (127–241)

 TC (mg/dL)

204 (175-232)

211 (181-235)

Blood pressure (mmHg)

137/80

137/80

Blood glucose

  

 HbA1c (%)

7.4 (6.8–8.3)

7.4 (6.8–8.2)

 FPG (mg/dL)

142 (119–171)

141 (119–169)

 PPG (mg/dL)

185 (155–221)

183 (155–220)

Hypoglycaemia requiring assistance (%)

1.2

1.4

Concomitant disease (%)

  

 Prior MI (%)

6.0

5.8

 Prior stroke/TIA (%)

4.6

4.8

 HF (%)

9.9

9.9

 PAD (%)

6.0

6.2

 Prior amputation (%)

0.9

0.9

 Any neuropathy (%)

15.9

14.5

 Any retinopathy (%)

4.2

4.2

 Vascular disease (%)**

24.0

24.3

Cardiovascular pharmacotherapy

  

 ACEi

50.0

50.5

 ARB

21.8

21.9

 Betablocker

46.6

46.5

 CCB

24.9

25.4

 Diuretic

41.2

42.0

 ASA

33.6

33.8

 Statin

42.2

42.6

Antidiabetic therapy post baseline

  

 Metformin (%)

84.5

84.5

 Sulfonylureas (%)

26.2

27.2

 Glucosidase inhibitors (%)

2.3

2.6

 Glinides (%)

6.0

5.3

 DPP-4 inhibitors (%)

38.8

39.3

 Glitazones (%)

10.3

10.1

 GLP-1 analogues (%)

9.2

9.7

 Insulin (%)

17.3

17.6

  1. Legend: *Including those that died during follow-up; **vascular disease includes CAD, prior stroke/TIA, and/or PAD; FU, follow-up; TG, triglycerides; FPG, fasting plasma glucose; PPG, postprandial plasma glucose; MI, myocardial infarction; TIA, transitory ischemic attack; HF, heart failure; PAD, peripheral artery disease; ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; CCB, calcium channel blocker; ASA, acetylsalicylic acid; DPP, dipeptidylpeptidase; GLP, glucagon-like peptide; SU, sulfonylurea.