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Table 1 Biometric and echocardiographic parameters

From: Chronic high-fat diet-induced obesity decreased survival and increased hypertrophy of rats with experimental eccentric hypertrophy from chronic aortic regurgitation

  Sham Ctrl Sham HF AR Ctrl AR HF
Tibia, mm 60.3 ± 0.64 61.4 ± 0.31 61.0 ± 0.43 61.0 ± 0.56
LV, mg 1163 ± 34.0 1225 ± 34.2 1823 ± 77.0a 2046 ± 69.9a, c
EDD, mm 8.4 ± 0.14 8.5 ± 0.17 11.4 ± 0.18a 11.6 ± 0.18a
ESD, mm 3.8 ± 0.22 3.8 ± 0.20 6.7 ± 0.17a 6.6 ± 0.22a
EF,% 78.6 ± 1.81 80.1 ± 1.52 64.8 ± 1.05a 67.9 ± 1.63a
RWT 0.30 ± 0.005 0.29 ± 0.005 0.23 ± 0.005a 0.21 ± 0.005a
kCal/day 126 ± 4.0 130 ± 4.0 126 ± 2.3 134 ± 4.1
TG, mmol/l 1.1 ± 0.12 1.1 ± 0.12 1.4 ± 0.14 1.0 ± 0.11
Chol., mmol/l 3.1 ± 0.46 2.9 ± 0.12 2.6 ± 0.13 3.1 ± 0.17
Gluc., mmol/l 17.4 ± 1.53 17.3 ± 1.72 15.9 ± 1.19 15.0 ± 1.05
Insulin, μg/l 1.4 ± 0.25 1.1 ± 0.19 1.6 ± 0.21a 2.4 ± 0.70a
Leptin, mg/l 1.1 ± 0.17 2.0 ± 0.22b 0.7 ± 0.13 2.1 ± 0.22b
Adiponectin, mg/l 10.4 ± 0.76 10.4 ± 0.69 7.7 ± 0.34 10.4 ± 0.76c
  1. Echo measurements obtained under 1.5% isoflurane anesthesia. LV left ventricle, EDD end-diastolic diameter, ESD end-systolic diameter, EF ejection fraction and RWT relative wall thickness. Animal daily food intake (kCal/day) and plasma levels of glucose, triglycerides, insulin, leptin and adiponectin plasma levels were estimated in animals sacrificed at 60 days post-AR. a: p < 0.001 versus sham groups, b: p < 0.01 vs. control diet groups and c: p < 0.01 vs. corresponding AR group by Bonferroni post-test. HF: high-fat diet.