Impact of a high-fat diet on FAO in chronic eccentric LV hypertrophy. HADH (A; hydroxyacyl-Coenzyme A dehydrogenase) and MCD (B; malonyl-CoA decarboxylase) enzymatic activities were measured as described in the Materials and Methods. In panel C, evaluation by real-time quantitative RT-PCR of the LV mRNA levels of genes related to FAO. Sham group mRNA levels were normalized to 1 and are represented as a black line on the graph. *: p < 0.05 and ***: p < 0.001 between sham and AR groups. §: p < 0.05, §§: p < 0.01 and §§§: p < 0.001 vs. corresponding sham or AR group.