Figure 5
Effects of reduced β 2 GP I on aortic MMP2, TIMP-1, and TIMP-2 protein expression levels. Aorta was sampled at day 22 (mono-dose groups) and day 43 (complex-dose groups) with ten aortas selected from each group after treatment and then assessed by Western Blotting. β-Tublin was selected as the internal control. A. MMP2. B. TIMP-1. C. TIMP-2. D. MMP2/TIMP-2. * P < 0.05 vs. normal controls; # P < 0.05 vs. diabetic controls; @ P < 0.05 vs. reduced β2GP I (R-β2GP I); and &P < 0.05 vs. β2GP I.