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Table 4 Univariate Cox regression analysis of event-free survival

From: Quantifying late gadolinium enhancement on CMR provides additional prognostic information in early risk-stratification of nonischemic cardiomyopathy: a cohort study

 

HR

95% CI

p-value

Demographics

   

 Age, year

1.020

0.980 - 1.060

0.333

 Gender, female

1.094

0.397 - 3.016

0.863

Symptoms

   

 Syncope or presyncope

1.093

0.348 - 3.434

0.879

 Palpitation

1.369

0.497 - 3.777

0.544

 Chest pain

0.837

0.286 - 2.449

0.745

 NYHA-class (III - IV)

2.820

1.003 - 7.928

0.049

Congestive heart failure

2.704

0.924 - 7.913

0.069

Arrhythmias

   

 Atrial fibrillation

2.256

0.818 - 6.223

0.116

 Ventricular fibrillation

0.559

0.073 - 4.250

0.574

 Sustained VT

3.807

1.207 - 12.013

0.023

 Nonsustained VT

1.122

0.317 - 3.975

0.859

Conducting abnormalities

   

 AVB of any grade

3.801

1.210 - 11.945

0.022

 Distal AVB

0.758

0.100 - 5.764

0.789

Cardiac enzyme elevation*

1.540

0.558 - 4.247

0.404

CMR

   

 LVEDV, ml/m2

1.004

0.991 - 1.016

0.556

 LVESV, ml/m2

1.008

0.996 - 1.020

0.213

 SV, ml

0.968

0.940 - 0.997

0.032

 LVEF, %

0.959

0.930 - 0.990

0.009

 LVEF < 50%

3.813

1.213 -11.981

0.022

 LGE, presence

6.329

0.832 - 48.143

0.075

 LGE, extent, score

1.042

1.019 - 1.065

< 0.001

 LGE, extent, % LV volume

1.028

1.013 - 1.044

< 0.001

 SWMA, presence**

  

0.002

 SWMA, extent, score

1.067

1.014 - 1.122

0.012

  1. *Troponin T, Troponin I or CK-mb.
  2. **HR was not calculated for the presence of SWMA, since there were no events in the group of patients without SWMA; Univariate p-value was walculated with Log rank test.
  3. Abbreviations: AVB atrioventricular block, CAD coronary artery disease, CI confidence interval, CMR cardiovascular magnetic resonance, HR hazard ratio, LV left ventricular, LVEF left ventricular ejection fraction, LGE late gadolinium enhancement, LVEDD left ventricle end-diastolic diameter, LVEDV left ventricle end-diastolic volume, LVESV left ventricle end-systolic volume, NYHA-class New York Heart Association classification of functional capacity, SV stroke volume, SWMA segmental wall motion abnormality, VT ventricular tachycardia.