Blood pressure values and depression in hypertensive individuals at high cardiovascular risk

Table 2 Log-linear model coefficients of systolic and diastolic blood pressure according to depression level and adjusted co-variables

	Natural logarithm of systolic blood pressure(mmHg)^†				Natural logarithm of diastolic blood pressure(mmHg)^‡
	Coefficients^§	Lower CI 95%^§	Upper CI 95%^§	P-value	Coefficients^§	Lower CI 95%^§	Upper CI 95%^§	P-value
Depression level
No Depression	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref
Untreated depression^a	-1.59	-2.69	-0.50	0.004	-0.59	-1.64	0.462	0.272
Treated depression^b	-3.49	-4.87	-2.10	0.001	-0.85	-2.18	0.49	0.213
Anti-Anxiety or sedative treatment ^c	-0.82	-1.66	0.02	0.056	-0.18	-0.99	0.62	0.657
Age (years)	0.25	0.20	0.31	0.001	-0.37	-0.42	0-.32	0.001
Sex (Women)	-2.60	-3.46	-1.75	0.001	-2.62	-3.44	-1.79	0.001
Educational attainment
High level	Ref	Ref	Ref	Ref	Ref	Ref	Ref	Ref
Middle level	0.96	-0.45	2.37	0.183	1.09	-0.27	2.44	0.117
Low level	0.13	-1.12	1.38	0.841	-0.42	-1.62	0.78	0.491
Body Mass Index( Kg/m ² )	0.24	0.16	0.33	0.001	0.42	0.34	0.50	0.001
Smoking ^d	-0.80	-1.65	0.05	0.064	-0.76	-1.57	0.05	0.067
Low adherence to the MeDiet pattern ^e	0.11	-0.56	0.78	0.746	-0.01	-0.65	0.64	0.989
Sedentary ^f	0.17	-0.46	0.80	0.600	-0.07	-0.68	0.54	0.816
High alcohol intake ^g	0.64	-0.17	1.45	0.122	0.72	-0.06	1.50	0.069
Diabetes ^h	1.28	0.62	1.94	0.001	-1.94	-2.57	-1.30	0.001
Dyslipidemia ⁱ	-0.34	-0.34	0.41	0.370	-0.60	-1.31	0.12	0.104
Antihypertensive treatment ^j	0.55	-0.26	1.37	0.182	0.46	-0.32	1.24	0.252

^aDiagnosis of depression and not taking any antidepressant drugs.
^bDiagnosis of depression and taking at least one of the following drugs: Selective serotonin reuptake inhibitors, non-selective monoamine reuptake inhibitors, Monoamine oxidase A inhibitors, antidepressants in combination with psycholeptics, others antidepressant agents.
^cTaking at least one of the following drugs: benzodiazepine derivatives, azaspirodecanedione derivatives, GABA (gamma-aminobutyric acid) analogues, natural antianxiety agents, ethanolamine derivatives, other anxiolytics, hypnotics and sedatives agents.
^dCurrent smoker.
^eAdherence to Mediterranean diet pattern < 9 points (median) on a scale of 0–14.
^fPhysical activity in leisure time < 1000 kcal/week in last year.
^gAlcohol consumption more than 20gr. daily in men and 10 gr. daily in women.
^hDiagnosis of diabetes.
ⁱDiagnosis of dyslipidaemia.
^jTaking at least one of the following antihypertensive drugs: angiotensin-converting-enzyme inhibitor (ACE inhibitors), diuretics, calcium channel blockers, angiotensin II receptor antagonists, Beta-blockers, α-blockers, or other antihypertensive drugs.
^†Kolmogorov-Smirnov Test (p value): 0.271.
^‡Kolmogorov-Smirnov Test (p value): 0.56.
^§Coefficients values multiplied by 100.

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