Skip to main content

Table 1 Clinical characteristics of family 6652

From: Whole-exome sequencing in an extended family with myocardial infarction unmasks familial hypercholesterolemia

Family ID

Pedigre ID

Sex$

BMI (kg/m2)

Age at first MI (years)

Age at first CAD (years)

LDL-C (mg/dL)

Statin therapy

Daily dose

Hyper-cholesterol-emia1#

Hyper-tension2#

Diabetes3#

Smoking4#

6652501

III.2

2

28.5

 

58

252

Atorvastatin

20

1

1

2

1

6652502

III.3

1

26.5

 

55

214

Atorvastatin

60

1

1

2

2

6652505

III.16

2

22.8

  

186

  

2

1

2

2

6652506

III.18

2

25.0

 

55

233

Atorvastatin

80

1

2

2

1

6652509

IV.6

2

26.4

  

184

  

2

2

2

1

6652511

III.6

1

25.9

44

67

189

Atorvastatin

10

1

1

2

1

6652512

III.20

1

30.5

  

136

Cerivastatin

0.3

1

1

2

2

6652513

IV.3

1

24.2

  

96

  

2

2

2

2

6652515

IV.5

2

23.4

  

171

  

2

2

2

1

6652516

IV.7

1

25.2

 

59

188

Atorvastatin

40

1

2

2

2

6652518

III.13

2

27.3

  

156

  

2

2

2

1

6652520

IV.9

1

22.5

  

142

Simvastatin

10

1

 

2

2

6652522

IV.13

1

29.4

  

166

  

2

2

2

1

6652523

IV.14

2

24.2

  

168

  

2

2

2

2

6652524

IV.15

2

23.5

  

130

  

2

 

2

2

6652525

IV.16

1

22.7

  

145

  

2

2

2

2

6652527

IV.20

2

23.4

  

143

  

2

 

2

1

6652531

IV.10

2

20.9

  

116

Atorvastatin

60

1

2

2

2

6652533

IV.12

2

21.3

      

2

2

2

6652534

III.19

1

23.1

  

115

  

2

1

2

2

6652535

IV.17

1

23.2

  

184

  

2

2

2

2

6652536

IV.18

1

22.8

  

274

Atorvastatin

20

1

2

2

2

  1. $:1 = male, 2 = female; #: 1 = yes, 2 = no; 1Blood pressure >140/90 mm Hg; 2LDL cholesterol > 190 mg/dL or statin therapy; 3History of diabetes mellitus; 4History of smoking. Index patient IV.7 in bold.
Back to article page

BMC Cardiovascular Disorders

ISSN: 1471-2261

Contact us