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Table 3 The association of visceral adipose tissue with HOMA-IR, and Hs-CRP in subjects without overt diabetes (N = 512)

From: High pericardial and peri-aortic adipose tissue burden in pre-diabetic and diabetic subjects

  PCF (ml) TAT (ml)
HOMA_IR hs-CRP HOMA_IR hs-CRP
  β-Coef. (p value) β-Coef. (p value) β-Coef. (p value) β-Coef. (p value)
  Un-adjusted Model 0.21 (<0.001) 0.16 (0.005) 0.43 (<0.001) 0.27 (<0.001)
Adjusted for BMI     
  Age, gender, BMI 0.11 (0.089) 0.12 (0.582) 0.42 (<0.001) 0.17 (0.021)
  Age, gender, BMI, Clinical variables 0.08 (0.266) 0.14 (0.373) 0.36 (0.005) 0.22 (0.024)
Adjusted for BSA     
  Age, gender, BSA 0.1 (0.056) 0.18 (0.057) 0.43 (<0.001) 0.19 (0.006)
  Age, gender, BSA, Clinical variables 0.05 (0.472) 0.08 (0.381) 0.36 (<0.001) 0.20 (0.026)
Adjusted for WC     
  Age, gender, WC 0.06 (0.387) 0.11 (0.034) 0.41 (<0.001) 0.12 (0.002)
  Age, gender, WC, Clinical variables 0.05 (0.514) 0.06 (0.482) 0.38 (<0.001) 0.20 (0.038)
Adjusted for body fat %     
  Age, gender, body fat % 0.14 (0.049) 0.13 (0.659) 0.46 (<0.001) 0.22 (0.002)
  Age, gender, body fat %, Clinical variables 0.09 (0.209) 0.13 (0.138) 0.40 (<0.001) 0.25 (0.007)
  1. BMI body mass index, HbA1c glycosylated hemoglobin, TG triglyceride, LDL cholesterol low-density cholesterol, HDL cholesterol high-density cholesterol, eGFR estimated glomerular filtration rate, WC waist circumference.
  2. Clinical variables included age, sex, systolic blood pressure, fasting glucose, triglyceride, HDL cholesterol, exercise, alcohol use, smoking, and hypertension or hyperlipidemia treatment.