From: High pericardial and peri-aortic adipose tissue burden in pre-diabetic and diabetic subjects
 | No diabetes | Pre-DM | DM |  |
---|---|---|---|---|
N = 357 | N = 155 | N = 50 | Trend P | |
Age | 47.5 ± 7.7 | 51 ± 8* | 53.5 ± 8* | <0.001 |
Gender, female | 127 (35.6%) | 22 (14%) | 12 (24%) | <0.001 |
SBP, mmHg | 116.9 ± 15.4 | 124.6 ± 16.8* | 130.2 ± 16.7* | <0.001 |
BMI, kg/m2 | 23.6 ± 3.1 | 25.3 ± 3.1* | 26.2 ± 3.8* | <0.001 |
BSA, m2 | 1.72 ± 0.17 | 1.8 ± 0.16 | 1.81 ± 0.15 | <0.001 |
WC, cm | 81 ± 8.9 | 86.9 ± 8.3* | 89.2 ± 8.7* | <0.001 |
Body Fat, % | 24.9 ± 6.2 | 25.9 ± 6.2 | 27.3 ± 9.1* | 0.08 |
PCF, ml | 68.2 ± 25.5 | 86.8 ± 26.9 | 91 ± 24.1 | 0.005 |
TAT, ml | 6.4 ± 3.3 | 8.7 ± 4.2 | 9.5 ± 3.2 | 0.005 |
Hypertension | 30 (7.7%) | 27 (17.5%) | 17 (34%) | <0.001 |
Hyperlipidemia | 14 (3.6%) | 9 (5.8%) | 5 (10%) | 0.157 |
Smoking | 83 (21.3%) | 38 (24.7%) | 16 (32%) | 0.172 |
Fasting Glucose, mg/dL | 91.6 ± 5.7 | 103.6 ± 8.6* | 159.7 ± 52.7*¥ | <0.001 |
Post-prandial Glucose, mg/dL | 99.3 ± 15.7 | 117.5 ± 30.1* | 205.2 ± 85.9*¥ | <0.001 |
HbA1c, % | 5.67 ± 0.32 | 5.93 ± 0.41* | 7.52 ± 1.85*¥ | <0.001 |
HOMA-IR | 1.25 ± 0.85 | 1.81 ± 1.09* | 3.42 ± 2.2*¥ | <0.001 |
Uric Acid, mg/dL | 5.58 ± 1.37 | 6.35 ± 1.48* | 6.04 ± 1.28Υ | <0.001 |
Total Cholesterol, mg/dL | 192.5 ± 33.9 | 195.1 ± 31.9 | 191.2 ± 39.7 | 0.79 |
TG, mg/dL | 126.4 ± 65.1 | 145.3 ± 85.6* | 204.6 ± 158.5*¥ | <0.001 |
LDL cholesterol, mg/dL | 125.2 ± 31 | 128.8 ± 31 | 122.8 ± 32 | 0.67 |
HDL cholesterol, mg/dL | 53.5 ± 13.5 | 49.8 ± 13.4* | 44.1 ± 9.3*¥ | <0.001 |
BUN, mg/dL | 11.9 ± 3.6 | 12.6 ± 3.4 | 13.1 ± 3.7Υ | <0.001 |
eGFR, mL/min/1.73 m2 | 86.9 ± 14.4 | 81.5 ± 13.3* | 84.8 ± 20.2 | 0.31 |