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Table 2 Effect of treatment with bosentan on echocardiographic parameters

From: Long-term results of treatment with bosentan in adult Eisenmenger’s syndrome patients with Down’s syndrome related to congenital heart disease

Parameter Baseline Final follow-up P valuea
RVSP from TR (mmHg) (n = 4) 94.0 ± 13.4 85.5 ± 7.6 0.3750
Peak velocity of PR (m/s) (n = 2) 4.00 ± 0.14 4.05 ± 0.07 1.0000
AcT (m/s) 62.9 ± 11.6 83.0 ± 9.6 0.0156
AcT/ET 0.24 ± 0.04 0.30 ± 0.02 0.0156
  1. RVSP: right ventricular systolic pressure; TR: tricuspid regurgitation; PR: pulmonary regurgitation; AcT: acceleration time; AcT/ET: acceleration/ejection time ratio; aWilcoxon signed-rank test.