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Table 3 Sensitivity, specificity and predicitve values of high sensitive troponin T and the combination of troponin and copeptin in the final diagnosis of ACS, NSTEMI and UAP

From: The combination of high sensitivity troponin T and copeptin facilitates early rule-out of ACS: a prospective observational study

  hsTnT ≤ 14 ng/L hsTnT ≤ 14 ng/L and Copeptin < 14 pmol/L p-value
ACS    
Sensitivity 69 (59-77) 83 (74-89) <0.001
Specificity 70 (65-75) 50 (45-55) <0.001
NPV 89 (84-92) 91 (86-94)  
PPV 40 (33-47) 32 (27-38)  
NSTEMI    
Sensitivity 87 (76-93) 96 (86-98) 0.031
Specificity 69 (65-74) 49 (44-54) <0.001
NPV 97 (94-98) 99 (95-99)  
PPV 32 (26-40) 24 (19-30)  
UAP    
Sensitivity 35 (20-52) 59 (42-74) 0.004
Specificity 61 (56-66) 43 (38-48) <0.001
NPV 92 (88-95) 93 (87-95)  
PPV 7 ( 4-12) 8 (5-12)  
  1. NPV negative predicitive value, PPV positive predicitive value, ACS acute coronary syndrome, NSTEMI non ST-elevation myocardial infarction, UAP unstable angina pectoris.
  2. Sensitivity, Specificity, NPV and PPV are given with corresponding 95% confidence interval.