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Table 3 Sensitivity, specificity and predicitve values of high sensitive troponin T and the combination of troponin and copeptin in the final diagnosis of ACS, NSTEMI and UAP

From: The combination of high sensitivity troponin T and copeptin facilitates early rule-out of ACS: a prospective observational study

 

hsTnT ≤ 14 ng/L

hsTnT ≤ 14 ng/L and Copeptin < 14 pmol/L

p-value

ACS

   

Sensitivity

69 (59-77)

83 (74-89)

<0.001

Specificity

70 (65-75)

50 (45-55)

<0.001

NPV

89 (84-92)

91 (86-94)

 

PPV

40 (33-47)

32 (27-38)

 

NSTEMI

   

Sensitivity

87 (76-93)

96 (86-98)

0.031

Specificity

69 (65-74)

49 (44-54)

<0.001

NPV

97 (94-98)

99 (95-99)

 

PPV

32 (26-40)

24 (19-30)

 

UAP

   

Sensitivity

35 (20-52)

59 (42-74)

0.004

Specificity

61 (56-66)

43 (38-48)

<0.001

NPV

92 (88-95)

93 (87-95)

 

PPV

7 ( 4-12)

8 (5-12)

 
  1. NPV negative predicitive value, PPV positive predicitive value, ACS acute coronary syndrome, NSTEMI non ST-elevation myocardial infarction, UAP unstable angina pectoris.
  2. Sensitivity, Specificity, NPV and PPV are given with corresponding 95% confidence interval.
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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