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Table 1 Baseline characterisctics and presentation in the study population and according to final diagnosis

From: The combination of high sensitivity troponin T and copeptin facilitates early rule-out of ACS: a prospective observational study

 

All

ACS

Not ACS

p-value

 

(n = 478)

(n = 107)

(n = 371)

(ACS vs not ACS)

General

    

Age (years)

66 (55-76)

68 (61-78)

65 (54-75)

0.012

Male sex

299 (63)

78 (73)

221 (60)

0.012

Medical history

    

Hypertension

256 (54)

69 (65)

187 (54%)

0.01

Hyperlipidemia and/or use of statins

185 (39)

54 (51)

131 (35)

0.005

Diabetes

99 (21)

27 (25)

72 (19)

0.19

Smokers

69 (17)

16 (16)

53 (17)

0.84

Ischemic heart disease

184 (39)

47 (44)

137 (37)

0.19

Prior PCI

101 (21)

24 (22)

77 (21)

0.71

Prior CABG

59 (12)

13 (12)

46 (12)

0.95

Stroke/TIA

52 (11)

12 (11)

40 (11)

0.9

Moderate to severe heart failure, EF < 35%

42 (9)

7 (7)

35 (9)

0.35

On presentation

    

Systolic blood pressure (mmHg)

146 (130-163)

155 (140-172)

143 (130-160)

<0.001

Diastolic blood pressure (mmHg)

80 (75-90)

85 (78-97)

80 (74-90)

0.007

Heart rate (beats/minute)

78 (68-90)

78 (67-89)

77 (69-91)

0.7

ST depression

36 (8)

18 (17)

18 (5)

<0.001

T-wave inversion

40 (8)

17 (16)

23 (6)

0.001

New LBBB

1

0

1

 

New RBBB

5

0

5

 

CRP (mg/L)

2.1 (0.8-6.7)

2.2 (0.9-4.8)

2.0 (0.76-6.9)

0.87

Creatinine (μg/L)

84 (70-100)

89 (77-107)

82 (69-97)

0.002

Cholesterol (mmol/L)

4.6 (3.7-5.4)

4.6 (3.9-5.5)

4.6 (3.3-5.4)

0.47

GRACE score

104 (82-132)

115 (96-137)

103 (78-130)

0.002

Copeptin (pmol/L)

12 (7-21)

16 (9-30)

12 (7-19)

<0.001

High sensitivity Troponin T (ng/L)

10 (5-25)

25 (13-84)

7 (5-18)

<0.001

  1. PCI percutaneus coronary intervention, CABG coronary artery bypass grafting, TIA transient ischemic attack, LBBB left bundle branch block, RBBB right bundle branch block, GRACE global registry of acute cardiac events. Data presented as n (%) of patients or median and 25th-75th interquartile range for continous variables.