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Table 1 Baseline characterisctics and presentation in the study population and according to final diagnosis

From: The combination of high sensitivity troponin T and copeptin facilitates early rule-out of ACS: a prospective observational study

  All ACS Not ACS p-value
  (n = 478) (n = 107) (n = 371) (ACS vs not ACS)
General     
Age (years) 66 (55-76) 68 (61-78) 65 (54-75) 0.012
Male sex 299 (63) 78 (73) 221 (60) 0.012
Medical history     
Hypertension 256 (54) 69 (65) 187 (54%) 0.01
Hyperlipidemia and/or use of statins 185 (39) 54 (51) 131 (35) 0.005
Diabetes 99 (21) 27 (25) 72 (19) 0.19
Smokers 69 (17) 16 (16) 53 (17) 0.84
Ischemic heart disease 184 (39) 47 (44) 137 (37) 0.19
Prior PCI 101 (21) 24 (22) 77 (21) 0.71
Prior CABG 59 (12) 13 (12) 46 (12) 0.95
Stroke/TIA 52 (11) 12 (11) 40 (11) 0.9
Moderate to severe heart failure, EF < 35% 42 (9) 7 (7) 35 (9) 0.35
On presentation     
Systolic blood pressure (mmHg) 146 (130-163) 155 (140-172) 143 (130-160) <0.001
Diastolic blood pressure (mmHg) 80 (75-90) 85 (78-97) 80 (74-90) 0.007
Heart rate (beats/minute) 78 (68-90) 78 (67-89) 77 (69-91) 0.7
ST depression 36 (8) 18 (17) 18 (5) <0.001
T-wave inversion 40 (8) 17 (16) 23 (6) 0.001
New LBBB 1 0 1  
New RBBB 5 0 5  
CRP (mg/L) 2.1 (0.8-6.7) 2.2 (0.9-4.8) 2.0 (0.76-6.9) 0.87
Creatinine (μg/L) 84 (70-100) 89 (77-107) 82 (69-97) 0.002
Cholesterol (mmol/L) 4.6 (3.7-5.4) 4.6 (3.9-5.5) 4.6 (3.3-5.4) 0.47
GRACE score 104 (82-132) 115 (96-137) 103 (78-130) 0.002
Copeptin (pmol/L) 12 (7-21) 16 (9-30) 12 (7-19) <0.001
High sensitivity Troponin T (ng/L) 10 (5-25) 25 (13-84) 7 (5-18) <0.001
  1. PCI percutaneus coronary intervention, CABG coronary artery bypass grafting, TIA transient ischemic attack, LBBB left bundle branch block, RBBB right bundle branch block, GRACE global registry of acute cardiac events. Data presented as n (%) of patients or median and 25th-75th interquartile range for continous variables.