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Table 1 Metabolic factors and carotid atherosclerosis in different blood pressure levels according to JNC-7

From: Prehypertension is associated with increased carotid atherosclerotic plaque in the community population of Southern China

  Normotension Prehypertension Hypertension P for trend
N 241 309 392 ----
Male/female 54/187 106/203 # 149/243 # <0.001
Age, years 55.5 ± 5.0 § 56.4 ± 5.5 #§ 58.9 ± 6.2 # <0.001
WC, cm 77.1 ± 7.9 § 82.4 ± 8.5 #§ 85.4 ± 9.1 # <0.001
WHR 0.85 ± 0.06 § 0.88 ± 0.07 #§ 0.90 ± 0.07 # <0.001
BMI, kg/m2 21.8 ± 3.0 § 23.5 ± 3.1 #§ 24.6 ± 3.3 # <0.001
SBP, mmHg 107.4 ± 7.8 § 124.2 ± 6.4 #§ 140.7 ± 15.2 # <0.001
DBP, mmHg 69.2 ± 5.7 § 78.5 ± 5.4 #§ 86.5 ± 10.3 # <0.001
PP, mmHg 38.3 ± 7.1 § 45.7 ± 8.1 #§ 54.2 ± 13.6 # <0.001
FBG, mmol/L 5.0 ± 1.1 § 5.1 ± 0.9 § 5.4 ± 1.4 # 0.001
TC, mmol/L 5.19 ± 0.96 5.28 ± 0.97 5.25 ± 1.00 0.487
TG, mmol/L 1.41 ± 0.78 § 1.74 ± 1.10 # 1.98 ± 2.06 # <0.001
LDL-C, mmol/L 3.53 ± 0.84 3.61 ± 0.88 3.65 ± 0.93 0.089
HDL-C, mmol/L 1.49 ± 0.34 § 1.39 ± 0.36 #§ 1.31 ± 0.32 # <0.001
DM, n (%) 13 (5.4) § 23 (7.4) § 54 (13.8) # <0.001
CHD, n (%) 4 (1.7) 8 (2.6) § 38 (9.7) # <0.001
IS, n (%) 0 (0.0) 4 (1.3) 14 (3.6) # 0.001
Smokers, n (%) 32 (13.3) § 59 (19.1) 82 (20.9) # 0.020
Alcohol, n (%) 13 (5.4) 25 (8.1) 32 (8.2) 0.230
WHO CO, n (%) 97 (40.2) § 179 (57.9) #§ 275 (70.2) # <0.001
Antihypertensive drugs, n (%) 0 (0.0) 0 (0.0) § 234 (59.7) # <0.001
Antidiabetic drugs, n (%) 11 (4.6) 17 (5.5) § 38 (9.7) # 0.022
Lipid-lowering drugs, n (%) 5 (2.1%) 5 (1.6) § 32 (8.2) # <0.001
  1. BP, blood pressure; WC, waist circumference; WHR, waist-to-hip ratio; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; PP, pulse pressure; FBG, fasting blood glucose; TC, total cholesterol; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; DM, diabetes mellitus; CHD, coronary heart diseases; IS, ischemic stroke; WHO CO, central obesity of WHO criteria; Values are unadjusted mean ± SD or number (%). P values are compared among the three/four groups by one-way ANOVA or χ 2 tests.
  2. # versus Normotension, p < 0.05; § versus Hypertension, p < 0.05.