Table 1 Inclusion and exclusion criteria

Inclusion criteria

Stable CAD (defined as previous MI, PCI, CABG > 6 months prior to inclusion or classic angina pectoris and positive angiogram/SPECT/CT-angiogram)

Age 45–75 years

BMI 28–40 kg/m²

Exclusion criteria

Known diabetes

Diabetes diagnosed at screening (repeated fasting plasma glucose ≥ 7 mM or Hba1c > 7%)

Severe or moderate valve disease

Main stem stenosis

Ejection Fraction < 35%

Physical or mental disability - expected to prevent completion of intervention

Severe COPD or asthma (FEV1 < 50% of expected)

Active cancer

Severe kidney (eGFR < 40 mL/hour) or severe liver disease

Severe ischemia or arrhythmias during exercise test

2. or 3. degree AV block, not protected by pacemaker

Organised training more than 2 times a week prior to inclusion

Significant weight loss or weight gain (> 5%) 3 month prior to inclusion