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Figure 2 | BMC Cardiovascular Disorders

Figure 2

From: In vitro and clinical studies examining the expression of osteopontin in cigarette smoke-exposed endothelial cells and cigarette smokers

Figure 2

Effects of PM treatment on osteopontin gene and protein expression. A, HUVECs from four different donors were exposed in triplicate experiments to 88 μg/ml PM for 24 h. Gene expression was examined using a PCR array. Data are mean fold changes in gene expression normalised to DMSO controls. B, 24-hour exposure to PM induced the secretion of osteopontin in a concentration dependent manner. Data are mean ± S.D. osteopontin concentrations (n = 6 in each case), as detected by electrochemiluminescence. *p < 0.05 compared to controls.

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