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Table 5 Effect of Doxorubicin, Vitamin E, and Telmisartan on rat serum catalase in IU/L

From: Vitamin E and telmisartan attenuates doxorubicin induced cardiac injury in rat through down regulation of inflammatory response

Groups

Catalase level IU/L

Percent of changing

Before treatment

After treatment

Ā 

Doxorubicin 15 mg./kg

0.06ā€‰Ā±ā€‰0.005

0.045ā€‰Ā±ā€‰0.003

-25%

Doxo. + Vit E 100 mg./kg

0.055ā€‰Ā±ā€‰0.004

0.047ā€‰Ā±ā€‰0.001

-14.5%

Doxo. + Telmisartan 1 mg./kg

0.057ā€‰Ā±ā€‰0.002

0.055ā€‰Ā±ā€‰0.008

-3.5%

  1. The values are expressed as meanā€‰Ā±ā€‰SEM. ā€  Pā€‰<ā€‰0.05, ā€ ā€  Pā€‰<ā€‰0.01 (means of each group after treatment versus their means before treatment) by using paired t test.
  2. * Pā€‰<ā€‰0.05, ** Pā€‰<ā€‰0.01 (means of Vitamin E, and Telmisartan groups after treatment versus means of Doxorubicin group after treatment) by using LSD test.