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Table 4 Association of ALDH2 genotypes with changes of systolic/diastolic blood pressure in SAPPHIRe cohort

From: Common ALDH2 genetic variants predict development of hypertension in the SAPPHIRe prospective cohort: Gene-environmental interaction with alcohol consumption

 

rs2238152

rs671

rs2158029

Estimate

P*

Estimate

P*

Estimate

P*

Δ systolic blood pressure

0.0564

0.86

0.865

0.0071

0.269

0.38

Δ diastolic blood pressure

0.0316

0.87

0.537

0.0026

0.0241

0.89

  1. Estimate: the changes in systolic/diastolic blood pressure associated with each additonal risk allele during follow-up.
  2. * adjusted for age, sex, alcohol intake, smoking, drugs, and physical activity. Corrections of blood pressure for antihypertensive drugs (10/5 mmHg reduction per drug) was made.