From: Heart Disease and Left Ventricular Rotation – A Systematic Review and Quantitative Summary
Study Details | Matched Controls | Apical Rotation | Basal Rotation | Twist | Torsion | Twist Rate | Time to Peak Twist | Time to Peak Untwist | Additional Notes |
---|---|---|---|---|---|---|---|---|---|
Govind et al. 2010 Case–control Level 3 D&B = 23 2D-STE*** | Yes | ↓ | ↓ | ↓ | Participants with MI and normal EF (>40%) had elevated twist and apical rotation rate as compared to participants with MI and low EF (<40%). | ||||
Bansal et al. 2008 Case–control Level 3 D&B = 17 2D-STE** | No | ↓ | ↓ | ↓ | Increasing number of infarcts was related to decreased basal rotation and torsion but not apical rotation. | ||||
Takeuchi et al. 2007 Case–control Level 3 D&B = 17 2D-STE** | Yes | ↔/↓ | ↔ | ↔/↓ | ↔/↓ | ↔ | ↔/↑ | Anterior MI participants were divided into those with normal (≥45%) and reduced (<45%) EF. Only reduced EF participants had reduced twist and apical rotation as well as time to peak untwist as compared to controls. | |
Nagel et al. 2000 Case–control Level 3 D&B = 15 MRI Tagging | No | ↓ | ↔ | ↔ | ↑ | Apical rotation is reduced in those with anterolateral MI but no difference between groups in mid level or basal rotation occurred. In a subgroup of anterolateral MI participants with accompanying LV aneurism, there is a complete loss of apical rotation and a reversal of mid level rotation that rotates with the base instead of the apex as in healthy controls. | |||
Garot et al. 2002 Case–control Level 3 D&B = 15 MRI Tagging | No | Only mid-ventricle (between apex and base) rotation was reported. Mid-ventricle rotation was reduced in those with MI. Those with normal EF (>48%) had higher rotation than those with low EF (<48%). | |||||||
Setser et al. 2007 Case–control Level 3 D&B = 14 MRI Tagging | No | ↔ | ↔ | ↓ | Ischemic cardiomyopathy/MI compared to healthy controls. |