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Table 1 Characteristics of study patients, overall and by sex

From: Relationships between high-sensitive C-reactive protein and markers of arterial stiffness in hypertensive patients. Differences by sex

Variable

Overall (n = 258)

Males (n = 153)

Females (n = 105)

P value

Age (years)

53.27 ± 12.01

52.18 ± 12.20

54,85 ± 11.60

0.080

Serum glucose (mg/dl)

87.69 ± 10.80

88.16 ± 11.53

86.99 ± 9.61

0.398

Glycated hemoglobin (%)

5.05 ± 0.54

5.06 ± 0.58

5.02 ± 0.48

0.566

Office BP (mmHg)

SBP

139.93 ± 16.75

141.35 ± 15.90

137.84 ± 17.81

0.099

DBP

88.34 ± 10.69

88.33 ± 10.53

88.37 ± 10.98

0.975

Pulse pressure

52.23 ± 12.82

53.61 ± 12.70

50.20 ± 12.79

0.036

Heart rate

72.37 ± 12.89

70.09 ± 12.62

75.74 ± 12.60

0.001

ABPM 24 hours (mmHg)

SBP

126.71 ± 12.83

127.66 ± 12.20

125.31 ± 13.63

0.149

DBP

78.72 ± 9.86

80.13 ± 9.58

76.65 ± 9.93

0.005

Pulse pressure

47.99 ± 9.50

47.53 ± 8.53

48.66 ± 10.76

0.348

Heart rate

71.92 ± 10.62

71.03 ± 11.47

73.24 ± 9.11

0.103

Home BP (mmHg)

SBP

127.23 ± 14.49

128.69 ± 13.55

125.11 ± 15.58

0.051

DBP

81.62 ± 9.85

81.92 ± 9.45

81.19 ± 10.43

0.557

Pulse pressure

45.60 ± 10.07

46.77 ± 9.01

43.91 ± 11.26

0.026

Heart rate

68.62 ± 9.17

67.35 ± 8.98

70.45 ± 9.18

0.007

Current smokers (%)

64 (24,8)

46 (30.1)

18 (17.1)

0.018

Obesity (%) *

70 (27,1)

45 (29.4)

25 (23.8)

0.320

BMI (kg/m2)

27.92 ± 3.83

28.30 ± 3.20

27.37 ± 4.55

0.054

Waist circumference (cm)

95.60 ± 11.12

99.45 ± 9.14

90.03 ± 11.41

p < 0.001

Dyslipidemia (%)

206 (79,8)

121 (79.1)

85 (81.0)

0.633

Total cholesterol (mg/dL)

208.96 ± 36.94

205.37 ± 35.13

214.27 ± 39.02

0.059

Triglycerides (mg/dL)

126.34 ± 73.35

135.95 ± 85.98

112.17 ± 45.96

0.011

LDL-cholesterol (mg/dL)

130.64 ± 33.00

129.59 ± 30.35

132.17 ± 36.62

0.546

HDL-cholesterol (mg/dL)

53.28 ± 13.01

48.90 ± 10.94

59.73 ± 13.16

p < 0.001

No HDL-cholesterol (mg/dL)

155,75 ± 36.48

156.50 ± 35.41

154.64 ± 38.15

0.692

Atherogénic Index

4,12 ± 1.13

4.39 ± 1.19

3.73 ± 0.92

p < 0.001

Cardiovascular risk DAgostino

15.29 ± 12.52

19.19 ± 14.15

9.55 ± 6.19

p < 0.001

hs-CRP (mg/L)

2.73 ± 4.02

2.94 ± 4.81

2.41 ± 2.37

0.310

Fibrinogen, g/L

317.05 ± 61.39

314.57 ± 63.55

320.69 ± 58.21

0.441

Maximum IMT (mm)

0.88 ± 0.14

0.90 ± 0.15

0.86 ± 0.11

0.012

Mean IMT (mm)

0.71 ± 0.12

0.73 ± 0.13

0.69 ± 0.10

0.011

PWV (m/sec)

8.65 ± 2.06

8.66 ± 2.14

8.64 ± 1.96

0.952

CAIx

30.12 ± 11.66

26.59 ± 11.45

35.31 ± 9.95

p < 0.001

PAIx

92.52 ± 21.19

85.97 ± 19.13

102.06 ± 20.47

p < 0.001

AASI

0.37 ± 0.06

0.37 ± 0.06

0.38 ± 0.06

0.050

AASI-BPVR

0.16 ± 0.16

0.15 ± 0.17

0.18 ± 0.13

0.101

Awake-AASI

0.37 ± 0.06

0.37 ± 0.05

0.38 ± 0.06

0.061

Sleep-AASI

0.38 ± 0.15

0.38 ± 0.14

0.39 ± 0.16

0.534

HASI

0.59 ± 0.18

0.58 ± 0.20

0.61 ± 0.15

0.365

HASI-BPVR

0.29 ± 0.24

0.25 ± 0.26

0.35 ± 0.19

0.001

Antihypertensive Drugs (%)

101 (39.1)

61 (39.9)

40 (38.1)

0.774

Lipid-lowering Drugs (%)

48 (18.6)

31 (20.3)

17 (16.2)

0.409

  1. Data for qualitative variables are expressed as n (%) and quantitative variables as mean ± standard deviation.
  2. * Obesity: BMI ≥ 30 Kg/m²or Waist circumference ≥ 88 cm in men and ≥ 102 cm in women. SBP: Systolic blood pressure; DBP: Diastolic blood pressure; AMBP: Ambulatory blood pressure monitoring; BMI, body mass index; hs-CRP: high-sensitive C-reactive protein; HDL, high density lipoprotein; LDL, lowdensity lipoprotein; IMT: Intima Media Thickness; PWV: pulse wave velocity; CAIx: Central augmentation index; PAIx: Peripheral augmentation index, AASI: Ambulatory arterial stiffness index, BPVR: Blood pressure variability ratio; HASI: Home arterial stiffness index.
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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