Table 1 Selected average parameters from pressure-volume loop study in the C3H/HeN and C3H/HeJ groups

Heart rate (bpm)

449.67 ± 2.29

392.44 ± 16.47

452 ± 16

448 ± 31

<0.05

End-systolic Volume (uL)

13.42 ± 0.25

45.23 ± 0.42

14.04 ± 0.38

21.28 ± 0.60

<0.05

End-diastolic Volume(uL)

35.25 ± 0.36

63.77 ± 0.51

34.90 ± 0.55

41.40 ± 0.54

<0.05

End-systolic pressure(mmHg)

123.8 ± 0.47

179.35 ± 3.40

122.3 ± 1.03

139.22 ± 1.04

<0.05

End-diastolic pressure(mmHg)

8.2 ± 0.58

97.40 ± 3.53

7.97 ± 0.09

15.28 ± 0.17

<0.05

Ejection Fraction (%)

61.91 ± 8.9

29.06 ± 1.05

63.14 ± 2.17

52.17 ± 2.56

<0.05

Cardiac Output (ml/min)

10.44 ± 4.54

5.03 ± 0.57

11.01 ± 0.30

9.84 ± 0.28

<0.05