Table 2 CTA diagnostic performance measures
Analysis level | No. of included studies a | Sensitivity % (95% CI) | Specificity % (95% CI) | PPV Median (range) | NPV Median (range) | Diagnostic accuracy Median (range) |
|---|---|---|---|---|---|---|
Patient: base case analysis | 18 | 98.2 (97.4-98.8) | 81.6 (79.0-84.0) | 90.5 (76-100) | 99.0 (83-100) | 92.0 (80-100) |
Patient: alternative analysis | 22 | 98.0 (97.2-98.6) | 83.2 (81.1-85.2) | 89.0 (63-100) | 98.0 (83-100) | 92.0 (80-100) |
Vessels: all | 17 | 94.9 (93.9-95.8) | 89.5 (88.8-90.2) | 75.0 (53-95) | 99.0 (93-100) | 91.5 (74-98) |
   RCA | 8 | 94.8 (92.0-96.9) | 91.0 (89.0-92.7) | 84.0 (73-94) | 98.5 (95-100) | 94.5 (84-99) |
   LM | 8 | 95.7 (85.2-99.5) | 97.1 (95.7-98.1) | 89.0 (24-100) | 100.0 (98-100) | 99.0 (91-100) |
   LAD | 7 | 97.4 (95.3-98.8) | 84.5 (82.1-86.7) | 78.0 (57-95) | 99.0 (95-100) | 93.0 (72-99) |
   CX | 8 | 94.1 (90.7-96.6) | 89.6 (87.7-91.3) | 78.5 (52-90) | 99.5 (95-100) | 94.0 (75-99) |
Segments: all | 17 | 91.3 (90.2-92.2) | 94.0 (93.7-94.2) | 69.0 (44-86) | 99.0 (98-100) | 95.5 (90-99) |