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Table 4 Unadjusted and adjusted odds ratios and 95 percent confidence intervals of acute myocardial infarction from 4 separate models.

From: Circulating Angiopoietins-1 and -2, Angiopoietin Receptor Tie-2 and Vascular Endothelial Growth Factor-A as Biomarkers of Acute Myocardial Infarction: a Prospective Nested Case-Control Study

Angiogenic factors

Minimally-adjusted*

Adjusted†

VEGF-A, 1 unit of Z score

1.13 (1.02-1.26)

1.01 (0.89-1.15)

Ang-2, 1 unit of Z score

1.31 (1.17-1.46)

1.17 (1.02-1.35)

Ang-1, 1 unit of Z score

0.98 (0.84-1.13)

0.95 (0.78-1.15)

Tie-2, 1 unit of Z score

1.19 (1.01-1.40)

0.79 (0.63-0.98)

  1. * Adjusted for matching factors (age, gender, race/ethnicity) by design
  2. † additional adjustment for diabetes, hypertension, smoking, alcohol consumption, BMI, LDL, HDL, triglycerides and CRP
  3. using a 50% random sample