Sex differences in the combined effect of chronic stress with impaired vascular endothelium functioning and the development of early atherosclerosis: The Cardiovascular Risk in Young Finns study

Table 4 The three-way interactions between sex, VE and FMD on carotid IMT and between sex, VE and CAC on carotid IMT

	R²*	R²change**	p	N
FMD responses
FMD x VE x sex¹	0.130	0.001	0.138	1602
#FMD x VE x sex¹	0.177	0.003	0.070	985
CAC responses
*CAC x VE x sex* ¹	*0.113*	*0.004*	*0.005*	*1715*
*#CAC x VE x sex* ₁	*0.159*	*0.006*	*0.006*	*1076*

Note. VE = vital exhaustion, FMD = flow-mediated dilatation (%), CAC = carotid artery compliance (%/10 mmHg).
¹ The main effects were included in each analysis, but they are not presented in the table.
*Calculated for the whole model.
**Refers to the interaction term.
#Additionally adjusted for cardiovascular risk factors: LDL-cholesterol, HDL-cholesterol, triglycerides, systolic and diastolic blood pressure.

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