Ventricular-arterial uncoupling in heart failure with preserved ejection fraction after myocardial infarction in dogs - invasive versus echocardiographic evaluation

Table 1 Echocardiographic data

	Baseline (n = 17)	Post MI (n = 17)	p value
Left ventricular remodeling
LVEDV, ml	29 ± 1	36 ± 2	< 0.001
LV mass, g	74 ± 3	95 ± 5	< 0.001
RWT	0.46 ± 0.01	0.36 ± 0.02	< 0.001
*Left ventricular systolic function*
LVEF, %	0.70 ± 0.01	0.57 ± 0.01	< 0.001
LVESV, ml	8.8 ± 0.6	15.5 ± 1.0	< 0.001
WMSI	1 ± 0.00	1.81 ± 0.06	< 0.001
S', m/s	0.109 ± 0.005	0.079 ± 0.003	< 0.001
FS, %	37 ± 1	33 ± 1	0.014
*Mitral inflow*
E, m/s	0.83 ± 0.03	0.77 ± 0.02	0.069
A, m/s	0.56 ± 0.02	0.64 ± 0.02	0.036
DT, s	0.079 ± 0.003	0.080 ± 0.001	0.838
E/A	1.51 ± 0.05	1.22 ± 0.05	< 0.001
*Mitral annulus displacement*
E', m/s	0.099 ± 0.008	0.074 ± 0.003	0.015
A', m/s	0.072 ± 0.005	0.074 ± 0.003	0.668
E'/A'	1.41 ± 0.12	1.03 ± 0.07	0.01
E/E'	8.4 ± 0.5	10.4 ± 0.6	0.044

Values are expressed as mean ± SEM. LV: left ventricle; EDV: end-diastolic volume; RWT: relative wall thickness; EF: ejection fraction; ESV: end-systolic volume; WMSI: wall motion score index; S': systolic myocardial velocity of septal mitral annulus; FS: fractional shortening; E and A: maximal velocities of the mitral E and A waves; DT: deceleration time of early mitral flow; E': early diastolic myocardial velocity of septal mitral annulus; A': late diastolic myocardial velocity of septal mitral annulus.

ISSN: 1471-2261