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Table 1 Baseline levels of subjects in the 12 studies included in the meta-analysis

From: Beneficial effects of time-restricted fasting on cardiovascular disease risk factors: a meta-analysis

Study

Participants

Study Design

Diet length

TRE Regimen (Fasting: Feeding)

Number of participants (comparator/control)

Plasma lipids (mmol/L)

Fasting Glucose (mmol/L)

Age (Year)

Sex (Female/Male)

Body Composition

Blood Pressure (mmHg)

Andriessen 2022

Adults with type 2 diabetes

RTC

3 weeks

14:10

14/14

N/A

7.9ā€‰Ā±ā€‰1.3

67.5ā€‰Ā±ā€‰5.2

7Ā F/7Ā M

BMI:30.5ā€‰Ā±ā€‰3.7

N/A

Anton 2019

Overweight, sedentary older adults

One group pretestā€“posttest design

4 weeks

16:08

10/10

N/A

5.87ā€‰Ā±ā€‰1.57

ā‰„ā€‰65

6Ā F/4Ā M

BMI:34.1ā€‰Ā±ā€‰3.3; WC:109.43ā€‰Ā±ā€‰12.9Ā cm

SBP:145.9ā€‰Ā±ā€‰15.6

DBP:78.1ā€‰Ā±ā€‰12.4

Brady 2021

Middle and long-distance runners

RTC

8 weeks

16:08

10/7

N/A

N/A

36.4ā€‰Ā±ā€‰7.4

17Ā M

Body mass:75.6ā€‰Ā±ā€‰9.3Ā kg; Fat mass:12.4ā€‰Ā±ā€‰4.3Ā kg; Height:1.79ā€‰Ā±ā€‰0.06Ā m

N/A

Cai 2019

NAFLD patients

RTC

4 weeks/12 weeks

16:08

95/79

TG:2.65ā€‰Ā±ā€‰1.69; LDL:2.55ā€‰Ā±ā€‰0.79; HDL:1.16ā€‰Ā±ā€‰0.50

5.09ā€‰Ā±ā€‰0.90

34.54ā€‰Ā±ā€‰6.96

145Ā F/52Ā M

BMI:26.34ā€‰Ā±ā€‰2.73; Fat mass:29.06ā€‰Ā±ā€‰3.64Ā kg

Lean mass:43.65ā€‰Ā±ā€‰3.95Ā kg; WC:92.59ā€‰Ā±ā€‰4.98Ā cm

N/A

Chiu 2022

Healthy male adults

RTC

5 days

16:08

8/8

TG:1.45ā€‰Ā±ā€‰0.70

3.94ā€‰Ā±ā€‰0.18

22ā€‰Ā±ā€‰1.3

8Ā M

BMI:26.0ā€‰Ā±ā€‰0.38

N/A

Chow 2020

Overweight adults

RTC

12 weeks

16:08

11/12

TG:0.98ā€‰Ā±ā€‰0.24

5.06ā€‰Ā±ā€‰0.72

45.5ā€‰Ā±ā€‰12.1

17Ā F/3Ā M

BMI 34.1ā€‰Ā±ā€‰7.5; Fat mass:45.6ā€‰Ā±ā€‰20.7Ā kg;

Lean Mass:51.1ā€‰Ā±ā€‰8.7Ā kg

SBP:123ā€‰Ā±ā€‰13

DBP:79ā€‰Ā±ā€‰8

Correia 2021

Healthy male physical education students

RTC

30 days

16:08

12/12

N/A

N/A

22.4ā€‰Ā±ā€‰2.8

12Ā M

BMI:24.2ā€‰Ā±ā€‰2.0; Body mass: 73.6ā€‰Ā±ā€‰9.5Ā kg

N/A

KesztyĆ¼s 2021

Healthy adults

One group pretestā€“posttest design

3 months

16:08

61/63

TG:1.31ā€‰Ā±ā€‰0.66; HDL:1.74ā€‰Ā±ā€‰0.39; LDL:3.48ā€‰Ā±ā€‰0.89

N/A

47.8ā€‰Ā±ā€‰10.5

53Ā F/8Ā M

BMI:26.1ā€‰Ā±ā€‰4.6 ;WC:89.1ā€‰Ā±ā€‰12.0Ā cm

N/A

Lin 2022

Middle-aged women

RTC

8 weeks

16:08

30/33

TG:1.22ā€‰Ā±ā€‰0.53; HDL:1.64ā€‰Ā±ā€‰0.31; LDL:2.79ā€‰Ā±ā€‰0.68

4.97ā€‰Ā±ā€‰0.48

54.2ā€‰Ā±ā€‰7.9

65Ā F

BMI:25.7ā€‰Ā±ā€‰3.8 ;WC:89.7ā€‰Ā±ā€‰9.5Ā cm

SBP:121.1ā€‰Ā±ā€‰12.9

DBP:71.2ā€‰Ā±ā€‰10

Moro 2016

Resistance trained males

RTC

8 weeks

16:08

17/17

TG:1.52ā€‰Ā±ā€‰0.18; HDL:1.40ā€‰Ā±ā€‰0.26; LDL:3.00ā€‰Ā±ā€‰0.30

5.34ā€‰Ā±ā€‰3.63

29.21ā€‰Ā±ā€‰3.8

34Ā M

Body mass:84.6ā€‰Ā±ā€‰6.2Ā kg; Fat mass:11.05ā€‰Ā±ā€‰4.27Ā kg

N/A

Peeke 2021

Adults with obesity

Two group pretestā€“posttest design

8 weeks

14:10; 12:12

30/30

N/A

5.64ā€‰Ā±ā€‰1.09

44ā€‰Ā±ā€‰11

26Ā F/4Ā M

BMI:38.9ā€‰Ā±ā€‰7.7

N/A

Zhao 2022

Adults with obesity

One group pretestā€“posttest design

8 weeks

14:10

15/15

TG:1.7ā€‰Ā±ā€‰0.6; HDL:1.06ā€‰Ā±ā€‰0.21

5.7ā€‰Ā±ā€‰0.4

63ā€‰Ā±ā€‰4

15Ā M

BMI:30.5ā€‰Ā±ā€‰2.4; WC:113ā€‰Ā±ā€‰4Ā cm

SBP:136ā€‰Ā±ā€‰19

DBP:83ā€‰Ā±ā€‰10