Skip to main content

Table 1 Baseline characteristic of HCM patients based on the presence of I-LGE on CMR

From: Focal ischemic myocardial fibrosis assessed by late gadolinium enhancement cardiovascular magnetic resonance in patients with hypertrophic cardiomyopathy

 

HCM with I-LGE

(Group 1, n = 22)

HCM with NI-LGE

(Group 2, n = 36)

HCM without LGE

(Group 3, n = 64)

ANOVA

(P-value)

Baseline characteristics

 Age, (years ± SD)

57.00 ± 12.90

58.47 ± 15.20

60.11 ± 15.32

0.320

 Males, n (%)

15 (68.18%)

20 (55.55%)

33 (51.56%)

0.399

 Height, cm

161.80 ± 7.21

159.9 ± 7.75

160.4 ± 8.33

0.807

 Weight, Kg

65.7 ± 9.92

62.61 ± 11.33

65.80 ± 13.33

0.470

 Hypertension, n (%)

10 (47.61%)

16 (50.00%)

36 (62.06%)

0.380

 Diabetes, n (%)

2 (10.00%)

5 (25.62%)

14 (24.13%)

0.320

 Alcohol, n (%)

7 (35.00%)

7 (21.87%)

15 (25.86%)

0.574

 Smoker, n (%)

8 (42.10%)

10 (31.25%)

17 (29.31%)

0.579

 Systolic blood pressure (mmHg)

124.40 ± 19.11

122.10 ± 15.27

123.70 ± 14.80

0.839

 Diastolic blood pressure (mmHg)

75,43 (67.00, 78.00)

67.88 ± 10.75

71.17 ± 9.52

0.181

 Heart rate (bpm)

74.91 ± 17.66

74.08 ± 13.86

73.79 ± 14.51

0.974

Laboratory data

 Hematocrit (%)

41.56 ± 5.35

40.51 ± 6.88

39.56 ± 7.19

0.804

 Blood glucose (mg/dL)

7.63 (2.28, 8.19)

6.43 (4.79, 6.39)

7.18 (5.17, 7.81)

0.337

 Hemoglobin A1c (mg/dL)

6.42 (5.50, 6.50)

5.81 (5.10, 6.15)

6.37 (5.67, 7.02)

0.086

 C-reactive protein (mg/dL)

13.08 (1.17, 4.00)

16.46 (1.00, 6.35)

9.98 (1.47, 7.5)

0.347

 NT-proBNP (pg/mL)

4857 (1101, 6596)

3078 (289.3, 3078)

1195 (155.9, 1093)

0.003

 BUN (umol/L)

7.00 (5.31, 7.04)

7.24 (4.93, 8.03)

7.06 (4.85, 9.07)

0.920

 Serum creatinine (umol/L)

79.36 (62.00, 87.35)

123.20 (63.95, 103.90)

72.71 (60.38, 78.25)

0.117

 Total cholesterol (mmol/L)

4.80 ± 0.83

4.79 ± 1.36

4.52 ± 1.21

0.262

 Triglyceride (mmol/L)

3.44 (0.98, 4.73)

2.66 (1.18, 2.78)

2.19 (1.09, 2.63)

0.747

 HDL-cholesterol (mmol/L)

1.20 (0.94, 1.32)

1.18 (1.00, 1.41)

1.38 (0.90, 1.36)

0.977

 Troponin I (ng/mL)

0.23 (0.001, 0.52)

0.15 (0.001, 0.01)

0.04 (0.001, 1.06)

0.395

 Myoglobin (ng/mL)

73.34 (37.47, 62.00)

65.81 (35.31, 65.40)

50.47 (33.89, 57.49)

0.803

 CK-MB (U/L)

14.63 (10.25, 16.50)

12.50 (9.00, 14.50)

12.86 (9.00, 15.25)

0.341

  1. HCM hypertrophic cardiomyopathy, I-LGE ischemic myocardial fibrosis assessed by late gadolinium enhancement, NI-LGE nonischemic myocardial fibrosis assessed by late gadolinium enhancement, CMR cardiovascular magnetic resonance, NT-proBNP N-terminal prohormone of the brain natriuretic peptide, CK-MB creatine kinase-MB