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Table 3 Predictors of inducible myocardial ischemia at univariate and multivariate analyses by logistic regression analysis in patients who underwent both cardiac stress tests and coronary angiography (n = 255)

From: Low HDL cholesterol and the eNOS Glu298Asp polymorphism are associated with inducible myocardial ischemia in patients with suspected stable coronary artery disease

 

Univariate analysis

OR (CI 95%), p-value

Multivariate analysis

OR (CI 95%), p-value

Age

1.0(1.0–1.1), p = 0.04

ns

Male sex

2.1(1.2–3.4), p = 0.008

ns

Family History of CAD

0.9(0.6–1.6), p = 0.9

-

High SBPa

1.3(0.8–2.2), p = 0.4

-

High LDL-C

0.7(0.4–1.1), p = 0.1

-

Smoking

1.1(0.6–2.0), p = 0.8

-

High BMIa

0.4(0.2–0.4), p = 0.001

0.3(0.1–0.5), p = 0.0005

High FPGa

0.8(0.5–1.2), p = 0.3

-

Low HDL-Ca

2.3(1.3–4.3), p = 0.007

ns

High TGa

1.5(0.9–2.7), p = 0.1

-

eNOS Asp genotype

1.9(1.2–3.0), p = 0.01

2.1(1.2–3. 7), p = 0.01

Obstructive CAD

4.3(2.6–7.4), p < 0.0001

3.1(1.67–5.8), p = 0.0004

  1. ns not significant, CAD coronary artery disease, high SBP (SBP = systolic blood pressure) SBP ≥ 130/85 mmHg or antihypertensive medication, high LDL-C (LDL-C = LDL cholesterol) LDL-C > 115 mg/dL, high BMI (BMI = body mass index) BMI > 30 kg/m2, high FPG (FPG = fasting plasma glucose) high FPG: diabetes or FPG > 100 mg/dL, low HDL-C (HDL-C = HDL cholesterol) HDL-C < 50 mg/dl in women and < 40 mg/dl in men or specific treatment for this lipid abnormality, high TG (TG = triglycerides) TG ≥ 150 mg/dl or specific treatment for this lipid abnormality
  2. acomponent of metabolic syndrome