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Table 2 Predictors of obstructive CAD or inducible myocardial ischemia at univariate and multivariate analyses by logistic regression analysis

From: Low HDL cholesterol and the eNOS Glu298Asp polymorphism are associated with inducible myocardial ischemia in patients with suspected stable coronary artery disease

 

Obstructive CAD

Inducible Myocardial Ischemia

 

Univariate analysis

OR (CI 95%), p-value

Multivariate analysis

OR (CI 95%), p-value

Univariate analysis

OR (CI 95%), p-value

Multivariate analysis

OR (CI 95%), p-value

Age

1.1 (1.0–1.1), p < 0.0001

1.1(1.0–1.11), p < 0.0001

1.1(1.0–1.1), p < 0.0001

ns

Male sex

4.0(2.6–6.3), p < 0.0001

4.8(2.9–8.1), p < 0.0001

4.0(2.6–6.3), p < 0.0001

1.9(1.1–3.1), p = 0.01

Family History of CAD

0.7(0.5–1.1), p = 0.09

ns

0.7(0.5–1.1), p = 0.09

ns

High SBPa

1.3(0.8–1.9), p = 0.1

ns

1.4(0.9–2.3), p = 0.1

ns

High LDL-C

0.7(0.5–1.1), p = 0.09

ns

0.6(0.4–0.9), p = 0.02

ns

Smoking

1.5(0.9–2.5), p = 0.07

ns

1.2(0.7–2.1), p = 0.5

-

High BMIa

0.6(0.4–1.0), p = 0.07

0.5(0.3–0.9), p = 0.03

0.4(0.2–0.7), p = 0.01

0.3(0.2–0.6), p = 0.0002

High FPGa

1.4(0.9–2.1), p = 0.06

ns

0.8(0.5–1.2), p = 0.3

-

Low HDL-Ca

2.5(1.6–3.7), p < 0.0001

2.8(1.7–4.7), p =  < 0.0001

1.9(1.1–3.2), p = 0.01

2.0(1.1–3.6), p = 0.04

High TGa

1.5(0.9–2.2), p = 0.09

ns

1.3(0.8–2.1), p = 0.3

-

eNOS Asp genotype

0.9(0.6–1.3), p = 0.6

-

1.9(1.2–3.0), p = 0.003

2.1(1.3–3.4), p = 0.003

  1. ns not significant, CAD coronary artery disease, high SBP (SBP = systolic blood pressure) SBP ≥ 130/85 mmHg or antihypertensive medication, high LDL-C (LDL-C = LDL cholesterol) LDL-C > 115 mg/dL, high BMI (BMI = body mass index) BMI > 30 kg/m2, high FPG (FPG = fasting plasma glucose) high FPG: diabetes or FPG > 100 mg/dL, low HDL-C (HDL-C = HDL cholesterol) HDL-C < 50 mg/dl in women and < 40 mg/dl in men or specific treatment for this lipid abnormality, high TG (TG = triglycerides) TG ≥ 150 mg/dl or specific treatment for this lipid abnormality
  2. acomponent of metabolic syndrome