Table 1 Endpoints reported in the original studies

Global Leaders [13]

All-cause mortality, MI, stroke, any revascularization, TVR, definite stent thrombosis, MACE, POCE, NACE, BARC 3c, BARC 2, 3 or 5 bleeding

1 month DAPT followed by ticagrelor monotherapy

24 months

Twilight [14]

Death, MI or stroke, cardiovascular death, MI or ischemic stroke, all-cause death, cardiac death, MI, ischemic stroke, stent thrombosis, TIMI minor or major; BARC 2,3 or 5 bleeding

3 months DAPT followed by ticagreglor monotherapy

12 months

Twilight DM CKD [15]

Death, MI or stroke, all-cause death, MI or ST, BARC 2, 3 or 5 bleeding

3 months DAPT followed by ticagrelor monotherapy

12 months

Tico [16]

All-cause mortality, cardiac death, MI, stent thrombosis, ischemic stroke, TVR, any revascularization, TIMI minor and TIMI major bleeding, fatal bleeding, BARC 3c

3 months DAPT followed by ticagrelor monotherapy

12 months