Table 4 Analysis of GO and KEGG enrichment of Mitophagy-DEGs
Term | Description | P Value | GeneID |
|---|---|---|---|
GO: BP | autophagy | 7.14143E-12 | Bcl2/Map1lc3b/Fbxw7/Rnf41/Sqstm1/Huwe1/Bnip3/Atg5/Gabarapl1/Vps13d/Prkaa2/Hif1a/Ubxn6/Clec16a/Atg14 |
GO: BP | macroautophagy | 1.1887E-12 | Map1lc3b/Rnf41/Sqstm1/Huwe1/Bnip3/Atg5/Gabarapl1/Vps13dPrkaa2/Hif1a/Ubxn6/Clec16a/Atg14 |
GO: BP | organelle disassembly | 3.78713E-15 | Map1lc3b/Fbxw7/Rnf41/Sqstm1/Huwe1/Bnip3/Atg5/Gabarapl1/Vps13d/Hif1a/Clec16a/Atg14 |
GO: BP | response to extracellular stimulus | 4.78674E-09 | Bcl2/Map1lc3b/Eif2s1/Eif2ak2/Mapk14/Atg5/Gabarapl1/Tfrc/Prkaa2/Plec/Clec16a/Atg14 |
GO: BP | myeloid cell differentiation | 9.23385E-09 | Prkdc/Plscr1/Fbxw7/Rnf41/Cnot4/Mapk14/Hspa1a/Tfrc/Hspa9/Abcb10/Hif1a/App |
GO: CC | myelin sheath | 2.54497E-06 | Hspd1/Bcl2/Phgdh/Atp6v1a/Rps27a/Hsp90aa1/Hspa9/Plec |
GO: CC | ribosome | 3.24078E-05 | Rps18/Rplp0/Rpl12/Rps27a/Rps3/Eef2/Rps15a |
GO: CC | early endosome | 0.000120211 | Hspd1/Vps35/Pi4k2a/Tfrc/Mon2/Ubxn6/App |
GO: CC | cytosolic ribosome | 9.54183E-06 | Rps18/Rplp0/Rpl12/Rps27a/Rps3/Rps15a |
GO: CC | autophagosome | 4.1545E-05 | Map1lc3b/Sqstm1/Atg5/Gabarapl1/Atg14 |
GO: MF | ubiquitin protein ligase binding | 2.85494E-10 | Hspd1/Bcl2/Arih1/Map1lc3b/Fbxw7/Sqstm1/Rps27a/Gabarapl1/Hspa1a/Hsp90aa1/Hspa9/Hif1a |
GO: MF | ubiquitin-like protein ligase binding | 2.85494E-10 | Hspd1/Bcl2/Arih1/Map1lc3b/Fbxw7/Sqstm1/Rps27a/Gabarapl1/Hspa1a/Hsp90aa1/Hspa9/Hif1a |
GO: MF | ATP hydrolysis activity | 3.78331E-05 | Hspd1/Abce1/Hspa1a/Hsp90aa1/Hspa9/Abcb10/Eif4a2 |
GO: MF | structural constituent of ribosome | 3.78331E-05 | Rps18/Rplp0/Rpl12/Rps27a/Rps3/Rps15a |
GO: MF | rRNA binding | 3.30564E-05 | Rps18/Rplp0/Rpl12/Rps3/Eef2 |
KEEG | Mitophagy—animal | 1.44545E-09 | Map1lc3b/Csnk2a1/Sqstm1/Rps27a/Bnip3/Atg5/Gabarapl1/Hif1a |
KEEG | NOD-like receptor signaling pathway | 9.20304E-05 | Bcl2/Map1lc3b/Mavs/Mapk14/Atg5/Gabarapl1/Hsp90aa1 |
KEEG | Ribosome | 0.00027538 | Rps18/Rplp0/Rpl12/Rps27a/Rps3/Rps15a |
KEEG | HIF-1 signaling pathway | 0.002645133 | Pfkp/Bcl2/Tfrc/Hif1a |
KEEG | RIG-I-like receptor signaling pathway | 0.005385165 | Mavs/Mapk14/Atg5 |