Table 3 Clinical characteristics and serum lipid-lipoprotein levels of T2DM + CAD patients stratified by APOE ɛ2, ɛ3, ɛ4 alleles
Variables | ε2 (ɛ2/ɛ2 + ɛ2/ɛ3) (n = 51) | ε3 (ɛ3/ɛ3) (n = 227) | ε4 (ɛ3/ɛ4 + ɛ4/ɛ4) (n = 88) | p values |
|---|---|---|---|---|
Age, years | Â | Â | Â | Â |
< 60, n(%) | 10(19.6) | 75(33.0) | 16(18.2) | 0.012 (χ2=8.899) |
≥ 60, n(%) | 41(80.4) | 152(67.0) | 72(81.8) | |
Gender | Â | Â | Â | Â |
Male, n(%) | 28(54.9) | 149(65.6) | 59(67.0) | 0.307 (χ2=2.429) |
Female, n(%) | 23(45.1) | 78(34.4) | 29(33.0) | |
BMI (kg/m2) | Â | Â | Â | Â |
< 18.5 | 3(5.9) | 15(6.6) | 1(1.1) | 0.335 (χ2=4.519) |
18.5–23.9 | 28(54.9) | 116(51.1) | 47(53.4) | |
≥ 24.0 | 20(39.2) | 96(42.3) | 40(45.5) | |
History of smoking, n(%) | 7(13.7) | 57(25.1) | 20(22.7) | 0.221 (χ2=3.056) |
History of alcoholism, n(%) | 0(0) | 15(6.6) | 3(3.4) | 0.106 (χ2=4.156) |
Serum lipid-lipoprotein levels | Â | Â | Â | Â |
TC, mmol/L | 4.49 ± 1.12 | 4.56 ± 1.36 | 4.74 ± 1.09 | 0.435 |
TG, mmol/L | 2.46 ± 1.60 | 2.11 ± 2.11 | 1.75 ± 0.92# | 0.076 |
HDL-C, mmol/L | 1.11 ± 0.29 | 1.11 ± 0.31 | 1.17 ± 0.32 | 0.311 |
LDL-C, mmol/L | 2.21 ± 0.84 | 2.43 ± 0.91 | 2.70 ± 0.76#* | 0.004 |
Apo-A1, g/L | 1.08 ± 0.21 | 1.04 ± 0.24 | 1.07 ± 0.23 | 0.299 |
Apo-B, g/L | 0.76 ± 0.26 | 0.82 ± 0.27 | 0.87 ± 0.23# | 0.049 |