Skip to main content

Table 1 Clinical characteristics of the subjects of this study

From: Apolipoprotein E E3/E4 genotype is associated with an increased risk of type 2 diabetes mellitus complicated with coronary artery disease

Variables

Total (n = 1160)

Controls (n = 351)

T2DM patients (n = 431)

T2DM complicated with CAD patients (n = 378)

p values

Age, years

     

< 60, n(%)

497(42.8)

219(62.4)

177(41.1)

101(26.7)

< 0.001

≥ 60, n(%)

663(57.2)

132(37.6)

254(58.9)

277(73.3)

Gender

     

Male, n(%)

754(65.0)

226(64.4)

285(66.1)

243(64.3)

0.831

Female, n(%)

406(35.0)

125(35.6)

146(33.9)

135(35.7)

BMI (kg/m2)

     

< 18.5

128(11.0)

94(26.8)

15(3.5)

19(5.0)

< 0.001

18.5–23.9

613(52.8)

197(56.1)

217(50.3)

199(52.6)

≥ 24.0

419(36.1)

60(17.1)

199(46.2)

160(42.3)

History of smoking, n(%)

245(21.1)

66(18.8)

92(21.3)

87(23.0)

0.376

History of alcoholism, n(%)

58(5.0)

23(6.6)

17(3.9)

18(4.8)

0.243

Serum lipid-lipoprotein levels

     

TC, mmol/L

4.47 ± 1.30

4.23 ± 1.15

4.56 ± 1.42

4.60 ± 1.26

< 0.001

TG, mmol/L

1.81 ± 1.63

1.33 ± 0.79

1.95 ± 1.86

2.10 ± 1.83

< 0.001

HDL-C, mmol/L

1.12 ± 0.36

1.17 ± 0.43

1.07 ± 0.32

1.12 ± 0.31

0.001

LDL-C, mmol/L

2.45 ± 0.86

2.36 ± 0.77

2.52 ± 0.90

2.46 ± 0.88

0.023

Apo-A1, g/L

1.03 ± 0.27

1.01 ± 0.32

1.01 ± 0.26

1.05 ± 0.23

0.046

Apo-B, g/L

0.80 ± 0.25

0.75 ± 0.23

0.83 ± 0.26

0.82 ± 0.26

< 0.001

  1. T2DM, type 2 diabetes mellitus; CAD, coronary artery disease; BMI, body mass index; Values for age expressed as mean ± SD. TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein-cholesterol; LDL-C, low-density lipoprotein-cholesterol; Apo-A1, apolipoprotein A1; Apo-B, apolipoprotein B